| Design of Modular G-quadruplex Ligands |
28 |
| Covalent Inhibition in Drug Discovery |
27 |
| Benzofuran and Indole: Promising Scaffolds for Drug Development in Alzheimer's Disease |
25 |
| Employing Photoredox Catalysis for DNA-Encoded Chemistry: Decarboxylative Alkylation of alpha-Amino Acids |
24 |
| Recent Advances in the Development of Indazole-based Anticancer Agents |
20 |
| TAS-120 Cancer Target Binding: Defining Reactivity and Revealing the First Fibroblast Growth Factor Receptor 1 (FGFR1) Irreversible Structure |
18 |
| Hollow Mesoporous Silica@Metal-Organic Framework and Applications for pH-Responsive Drug Delivery |
14 |
| The Curtius Rearrangement: Applications in Modern Drug Discovery and Medicinal Chemistry |
13 |
| Monosaccharide Derivatives with Low-Nanomolar Lectin Affinity and High Selectivity Based on Combined Fluorine-Amide, Phenyl-Arginine, Sulfur-pi, and Halogen Bond Interactions |
13 |
| Discovery and Mechanistic Elucidation of a Class of Protein Disulfide Isomerase Inhibitors for the Treatment of Glioblastoma |
13 |
| Inhibitors of Xanthine Oxidase: Scaffold Diversity and Structure-Based Drug Design |
12 |
| Ionic Liquids and Salts from Ibuprofen as Promising Innovative Formulations of an Old Drug |
12 |
| Synthesis and Anticancer Evaluation of 4-Naphthoquinone Derivatives Containing a Phenylaminosulfanyl Moiety |
12 |
| Discovery of Rogaratinib (BAY 1163877): a pan-FGFR Inhibitor |
12 |
| State of the Art of Pharmaceutical Solid Forms: from Crystal Property Issues to Nanocrystals Formulation |
12 |
| Identification of -Mangostin as an Agonist of Human STING |
12 |
| Identification and Optimization of 4-Anilinoquinolines as Inhibitors of CyclinG Associated Kinase |
12 |
| Discovery of Vilaprisan (BAY 1002670): A Highly Potent and Selective Progesterone Receptor Modulator Optimized for Gynecologic Therapies |
11 |
| Design and Synthesis of DNA-Interactive -Carboline-Oxindole Hybrids as Cytotoxic and Apoptosis-Inducing Agents |
11 |
| Synthesis and Evaluation of N-Phenylpyrrolamides as DNA GyraseB Inhibitors |
11 |
| Novel Peroxides as Promising Anticancer Agents with Unexpected Depressed Antimalarial Activity |
11 |
| Discovery of a Potent, Long-Acting, and CNS-Active Inhibitor (BIA 10-2474) of Fatty Acid Amide Hydrolase |
11 |
| In Silico Prediction of Blood-Brain Barrier Permeability of Compounds by Machine Learning and Resampling Methods |
11 |
| Antibody Fragment and Affibody ImmunoPET Imaging Agents: Radiolabelling Strategies and Applications |
11 |
| Histone Deacetylase Inhibitors as Multitarget Ligands: New Players in Alzheimer's Disease Drug Discovery? |
11 |
| Optimization of LpxC Inhibitors for Antibacterial Activity and Cardiovascular Safety |
10 |
| A DNA-Encoded Library of Chemical Compounds Based on Common Scaffolding Structures Reveals the Impact of Ligand Geometry on Protein Recognition |
10 |
| Targeting the BCL2 Gene Promoter G-Quadruplex with a New Class of Furopyridazinone-Based Molecules |
10 |
| Development of Potent Inhibitors of the Mycobacterium tuberculosis Virulence Factor Zmp1 and Evaluation of Their Effect on Mycobacterial Survival inside Macrophages |
10 |
| Niclosamide, a Drug with Many (Re)purposes |
10 |
| AquaMMapS: An Alternative Tool to Monitor the Role of Water Molecules During Protein-Ligand Association |
10 |
| Discovery of Molidustat (BAY85-3934): A Small-Molecule Oral HIF-Prolyl Hydroxylase (HIF-PH) Inhibitor for the Treatment of Renal Anemia |
10 |
| Glucagon-Like Peptide-1 (GLP-1)-Based Therapeutics: Current Status and Future Opportunities beyond Type2 Diabetes |
9 |
| 5-Triazino Peptide Derivatives: Synthesis, Characterization, and Preliminary Antileishmanial Activity |
9 |
| Auranofin and its Analogues Show Potent Antimicrobial Activity against Multidrug-Resistant Pathogens: Structure-Activity Relationships |
9 |
| Investigation of Dipicolinic Acid Isosteres for the Inhibition of Metallo-beta-Lactamases |
9 |
| The Outcomes of Decorated Prolines in the Discovery of Antimicrobial Peptides from Temporin-L |
9 |
| Designing Anticancer Peptides by Constructive Machine Learning |
9 |
| Preparation of Titanocene-Gold Compounds Based on Highly Active Gold(I)-N-Heterocyclic Carbene Anticancer Agents: Preliminary in vitro Studies in Renal and Prostate Cancer Cell Lines |
9 |
| Targeting an EGFR Water Network with 4-Anilinoquin(az)oline Inhibitors for Chordoma |
8 |
| Unpacking the Pathogen Box-An Open Source Tool for Fighting Neglected Tropical Disease |
8 |
| Synthesis, Biological Evaluation, and Molecular Docking of Combretastatin and Colchicine Derivatives and their hCE1-Activated Prodrugs as Antiviral Agents |
8 |
| Improvement of Aglycone pi-Stacking Yields Nanomolar to Sub-nanomolar FimH Antagonists |
8 |
| IChem: A Versatile Toolkit for Detecting, Comparing, and Predicting Protein-Ligand Interactions |
8 |
| Assembly of Fully Substituted 2H-Indazoles Catalyzed by Cu2O Rhombic Dodecahedra and Evaluation of Anticancer Activity |
8 |
| Design of Natural-Product-Inspired Multitarget Ligands by Machine Learning |
8 |
| An Endogenous Reactive Oxygen Species (ROS)-Activated Histone Deacetylase Inhibitor Prodrug for Cancer Chemotherapy |
8 |
| Axitinib: A Photoswitchable Approved Tyrosine Kinase Inhibitor |
7 |
| The Role of the Phosphorus Atom in Drug Design |
7 |
| In Silico Prediction of Compounds Binding to Human Plasma Proteins by QSAR Models |
7 |
