Letters In Drug Design & Discovery

Letters In Drug Design & Discovery

药物设计与发现快报

  • 4区 中科院分区
  • Q4 JCR分区

高引用文章

文章名称 引用次数
Synthesis, Biological Evaluation and Docking Studies of 4-oxadiazole Fused Benzothiazole Derivatives for Anticancer Drugs 15
Synthesis and Mosquiticidal Activity of Novel Hydrazone Containing Pyrimidine Derivatives against Aedes aegypti 13
Synthesis, Molecular Docking and Biological Evaluation of Mannich Products Based on Thiophene Nucleus using Ionic Liquid 11
Novel Trifluoromethylpyrazole Acyl Thiourea Derivatives: Synthesis, Antifungal Activity and Docking Study 11
Biological Activities and Docking Studies on Novel Bis 4-DHPS Linked to Arene Core via Ether or Ester Linkage 9
The Impacts of Some Sedative Drugs on alpha -Glycosidase, Acetylcholinesterase and Butyrylcholinesterase Enzymes-potential Drugs for Some Metabolic Diseases 8
Synthesis, Nematicidal Activity and Docking Study of Novel Pyrazole-4-carboxamide Derivatives Against Meloidogyne incognita 7
Synthesis and Antifungal Activity of Some 6-tert-butyl-8-chloro- 3-dimethylquinolin-4-ol Derivatives against Pyricularia oryae 7
Novel 4-Oxadiazole Fused Thiadiazole Derivatives: Synthesis and Study of Anticancer Activities 7
Synthesis and Antioxidant Evaluation of a New Class of Thienopyrimidine-rhodanine Hybrids 6
A Comprehensive Review on Recent Developments in the Field of Biological Applications of Potent Pyrazolines Derived from Chalcone Precursors 5
Design, Synthesis and Anti-tuberculosis Activity of Hydrazones and N-acylhydrazones Containing Vitamin B-6 and Different Heteroaromatic Nucleus 5
Design, Synthesis and Cytotoxicity of Novel Coumarin-3-triazole-4-Oxadiazole Hybrids as Potent Anti-breast Cancer Agents 5
Design, Synthesis and Characterization of Novel Urolithin Derivatives as Cholinesterase Inhibitor Agents 5
Design, Synthesis and Biological Evaluation of Novel Dihydropyrimidine-2-thione Derivatives as Potent Antimicrobial Agents: Experimental and Molecular Docking Approach 5
Molecular Dynamics and Inhibition of MERS CoV Papain-like Protease by Small Molecule Imidazole and Aminopurine Derivatives 4
Challenges in the Discovery and Optimization of mGlu(2/4) Heterodimer Positive Allosteric Modulators 4
Synthesis, Characterization and Antibacterial Evaluation of some New 4-triazolo[4-b][4]thiadiazines as Potential Antibacterial Agents 4
Neurokinin-1 Receptor Antagonists as Anticancer Drugs 4
Antimicrobial Activity and Molecular Docking of Tannins from Pimenta dioica 3
Investigation of Drug Interaction Potentials and Binding Modes on Direct Renin Inhibitors: A Computational Modeling Studies 3
Novel Azole-Functionalited Flouroquinolone Hybrids: Design, Conventional and Microwave Irradiated Synthesis, Evaluation as Antibacterial and Antioxidant Agents 3
N-Acetylserotonin vs Melatonin: In-Vitro Controlled Release from Hydrophilic Matrix Tablets 3
Design, Synthesis, and Screening of Hybrid Benzothiazolyl-oxadiazoles as Anticonvulsant Agents 3
Microwave-assisted Synthesis and Antifungal Activity of Novel 4-triazole Thioether Derivatives Containing Pyrimidine Moiety 3
Synthesis and Biological Activity of New Schiff Bases of Benzylideneamine Bearing Thiophene, 4-triazolone, 4-oxadiazole, Morpholine Moieties 3
6-Methoxy-4-dihydronaphthalenone Chalcone-like Derivatives as Potent Tyrosinase Inhibitors and Radical Scavengers 3
Synthesis and Antibacterial/Antitubercular/Antioxidant Activities of Compounds Containing Fluoroquinolone Ring Linked to a 4-thiazolidinone Moiety 3
Structure Guided Molecular Docking Assisted Alignment Dependent 3D-QSAR Study on Steroidal Aromatase Inhibitors (SAIs) as Anti-breast Cancer Agents 3
Dual Acting Isatin-heterocyclic Hybrids: Recent Highlights as Promising Pharmacological Agents 3
Novel Tri-substituted Thiazoles Bearing Piperazine Ring: Synthesis and Evaluation of their Anticancer Activity 3
Potential of Nanoparticles in Combating Candida Infections 3
alpha-Glucosidase Inhibition, Antioxidant and Docking Studies of Hydroxycoumarins and their Mono and Bis O-alkylated/acetylated Analogs 3
Design and Synthesis of Novel 4-oxadiazole Derivatives Bearing Azo Moiety as Biologically Significant Scaffolds 3
Synthesis and Biological Evaluation of New Quinoline-Based Thiazolyl Hydrazone Derivatives as Potent Antifungal and Anticancer Agents 2
The Development of Tyrosyl-DNA Phosphodyesterase 1 (TDP1) Inhibitors Based on the Amines Combining Aromatic/Heteroaromatic and Monoterpenoid Moieties 2
Design, Synthesis and Evaluation of Thiourea Derivatives as Antimicrobial and Antiviral Agents 2
Design and Synthesis of Novel Thiosemicarbazones as Potent Anti-breast Cancer Agents 2
A New Class of Pure Estrogen Alpha Receptor Antagonists; Design, Synthesis and In-vitro Screening 2
Synthesis, Biological Evaluation and Docking Studies of N-(2-benzamido feruloyl) Aryl Hydrazone Analogues 2
Monobactams: A Unique Natural Scaffold of Four-membered Ring Skeleton, Recent Development to Clinically Overcome Infections by Multidrug-resistant Microbes 2
Synthesis and Antimicrobial Activity of Adamantyl Substituted Pyridoxine Derivatives 2
Novel Hybrid Molecules of Isoxazole Chalcone Derivatives: Synthesis and Study of In Vitro Cytotoxic Activities 2
In Silico Study of Flavonoids as DPP-4 and alpha-glucosidase Inhibitors 2
Synthesis and Biological Evaluation of Some Pyrazole Derivatives, Containing (Thio) Semicarbazide, as Dual Anti-Inflammatory Antimicrobial Agents 2
Synthesis and Biological Evaluation of Some Novel Thiophene-bearing Quinazoline Derivatives as EGFR Inhibitors 2
Synthesis, Antimicrobial Evaluation and In silico Studies of Novel 4-disubstituted-3-thiazole Derivatives 2
Synthesis, Characterization, Free-radical Scavenging Capacity and Antioxidant Activity of Novel Series of Hydrazone, 4-oxadiazole and 4-triazole Derived from 5-dimethyl-1H-pyrazole 2
Synthesis, Antimicrobial Effect and Surface Properties of Hydroxymethyl-substituted Pyridinium Salts 2
Oral Bioavailability of Naturally Occurring Anticancer Phytomolecules 2