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Matrine protects human glomerular mesangial cells from lipopolysaccharide-induced Injury via the MCP-1/CCR2 axis and TLR4/NF-κB pathway in glomerulonephriti
Author: Wei, Huanbing; Dai, Yunfeng; Gao, Ying; Jia, Weiwei; Li, Ang
Journal: LETTERS IN DRUG DESIGN & DISCOVERY. 2026; Vol. 23, Issue 1, pp. -. DOI: 10.1016/j.lddd.2026.100346
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Unveiling biomarkers of chemoresistance: CASP1, ENG, and H6PD in 5-Fu-treated colorectal cance
Author: Huang, Xiang; Hua, Long; Ye, Junhao; Zhu, Lijun; Zhu, Yiping
Journal: LETTERS IN DRUG DESIGN & DISCOVERY. 2026; Vol. 23, Issue 1, pp. -. DOI: 10.1016/j.lddd.2026.100375
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Research progress on the mechanism and intervention strategies of MET protein in regulating the resistance to targeted therapy for EGFR-mutated non-small cell lung cance
Author: Chen, Fanghong; Zhang, Hangyue; Wang, Chengcheng; Liu, Menglan; Gao, Xudong; Wang, Jianxia; Shen, Li
Journal: LETTERS IN DRUG DESIGN & DISCOVERY. 2026; Vol. 23, Issue 1, pp. -. DOI: 10.1016/j.lddd.2026.100357
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Epigallocatechin gallate impels osteogenic differentiation of human BMSCs by targeting the METTL3/SATB2/Wnt/β-catenin axi
Author: Ren, Qiao; Chen, Kang; Wang, Lin
Journal: LETTERS IN DRUG DESIGN & DISCOVERY. 2025; Vol. 22, Issue 3, pp. -. DOI: 10.1016/j.lddd.2025.100027
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Efficacy analysis of Salmeterol Xinafoate and Fluticasone Propionate power for inhalation in treating pediatric asthma patient
Author: Zheng, Bojuan; Gao, Lianlian; Zhou, Liang; Li, Jinying; Tian, Liyuan; Yuan, Jie
Journal: LETTERS IN DRUG DESIGN & DISCOVERY. 2025; Vol. 22, Issue 2, pp. -. DOI: 10.1016/j.lddd.2025.100020
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Puerarin alleviates spinal cord injury by mediating the proliferation and activation of NG2 glial cell
Author: Ye, Ping; Liao, Xinyuan; Zhao, Yin; Zhou, Shengyuan; Guo, Xiang; Yang, Lili; Lv, Bitao
Journal: LETTERS IN DRUG DESIGN & DISCOVERY. 2025; Vol. 22, Issue 2, pp. -. DOI: 10.1016/j.lddd.2025.100011
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The mechanism of Peilian Ephehuang Prescription in the treatment of simple obesity based on network pharmacology and molecular docking technolog
Author: Wen, Nuan; Gu, Changrui; Zhao, Ying; Ma, Jian
Journal: LETTERS IN DRUG DESIGN & DISCOVERY. 2025; Vol. 22, Issue 2, pp. -. DOI: 10.1016/j.lddd.2025.100019
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Thymoquinone suppresses cell growth and induces ferroptosis in renal cell carcinoma by reducing SERPINH1 expressio
Author: Luo, Ruiying; Li, Shuang; Wang, Haohao; Zhang, Zuyu; Li, Long; Shang, Panfeng
Journal: LETTERS IN DRUG DESIGN & DISCOVERY. 2025; Vol. 22, Issue 2, pp. -. DOI: 10.1016/j.lddd.2025.100013
