Oncogene

Oncogene

癌基因

  • 1区 中科院分区
  • Q1 JCR分区

高引用文章

文章名称 引用次数
Circular RNAs in cancer: opportunities and challenges in the field 243
A novel protein encoded by the circular form of the SHPRH gene suppresses glioma tumorigenesis 98
Essential role of METTL3-mediated m(6)A modification in glioma stem-like cells maintenance and radioresistance 86
Dual role of autophagy in hallmarks of cancer 84
The m(6)A methyltransferase METTL3 promotes bladder cancer progression via AFF4/NF-kappa B/MYC signaling network 73
LncRNA PVT1 promotes angiogenesis via activating the STAT3/VEGFA axis in gastric cancer 71
Epidermal growth factor receptor and EGFRvIII in glioblastoma: signaling pathways and targeted therapies 67
Exosome circRNA secreted from adipocytes promotes the growth of hepatocellular carcinoma by targeting deubiquitination-related USP7 62
YAP1-induced MALAT1 promotes epithelial-mesenchymal transition and angiogenesis by sponging miR-126-5p in colorectal cancer 57
Adipocyte-induced CD36 expression drives ovarian cancer progression and metastasis 57
Mechanisms underlying the activation of TERT transcription and telomerase activity in human cancer: old actors and new players 53
Genetic, transcriptional and post-translational regulation of the programmed death protein ligand 1 in cancer: biology and clinical correlations 45
Immunosuppressive effects of hypoxia-induced glioma exosomes through myeloid-derived suppressor cells via the miR-10a/Rora and miR-21/Pten Pathways 44
Classifying BRAF alterations in cancer: new rational therapeutic strategies for actionable mutations 44
Tumor-derived exosomal lnc-Sox2ot promotes EMT and stemness by acting as a ceRNA in pancreatic ductal adenocarcinoma 40
LncRNA PVT1 regulates triple-negative breast cancer through KLF5/beta-catenin signaling 38
The ERK and JNK pathways in the regulation of metabolic reprogramming 38
Wild-type and mutated IDH1/2 enzymes and therapy responses 38
E-cadherin in contact inhibition and cancer 38
Hypoxia-induced LncRNA-BX111 promotes metastasis and progression of pancreatic cancer through regulating ZEB1 transcription 36
The dynamic and stress-adaptive signaling hub of 14-3-3: emerging mechanisms of regulation and context-dependent protein-protein interactions 35
Dynamic m(6)A mRNA methylation reveals the role of METTL3-m(6)A-CDCP1 signaling axis in chemical carcinogenesis 35
Pro-tumorigenic roles of fibroblast activation protein in cancer: back to the basics 35
Biological heterogeneity and versatility of cancer-associated fibroblasts in the tumor microenvironment 34
Connexins in cancer: bridging the gap to the clinic 34
MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer 33
The P2X7 receptor modulates immune cells infiltration, ectonucleotidases expression and extracellular ATP levels in the tumor microenvironment 33
WNT signaling modulates PD-L1 expression in the stem cell compartment of triple-negative breast cancer 32
Metastasis-associated miR-23a from nasopharyngeal carcinoma-derived exosomes mediates angiogenesis by repressing a novel target gene TSGA10 32
KIAA1429 acts as an oncogenic factor in breast cancer by regulating CDK1 in an N6-methyladenosine-independent manner 32
A circular RNA circ-DNMT1 enhances breast cancer progression by activating autophagy 32
Epithelial-mesenchymal transition (EMT) beyond EGFR mutations per se is a common mechanism for acquired resistance to EGFR TKI 32
Glycolysis gatekeeper PDK1 reprograms breast cancer stem cells under hypoxia 32
xCT (SLC7A11)-mediated metabolic reprogramming promotes non-small cell lung cancer progression 31
The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma 31
Exosomal Wnt-induced dedifferentiation of colorectal cancer cells contributes to chemotherapy resistance 31
Hypoxia-induced tumor exosomes promote M2-like macrophage polarization of infiltrating myeloid cells and microRNA-mediated metabolic shift 31
Epithelial-mesenchymal-transition-inducing transcription factors: new targets for tackling chemoresistance in cancer? 30
miR-137 mediates the functional link between c-Myc and EZH2 that regulates cisplatin resistance in ovarian cancer 29
miR-139-5p inhibits aerobic glycolysis, cell proliferation, migration, and invasion in hepatocellular carcinoma via a reciprocal regulatory interaction with ETS1 29
Cancer-associated fibroblasts promote prostate cancer malignancy via metabolic rewiring and mitochondrial transfer 29
Microenvironmental oxygen pressure orchestrates an anti- and pro-tumoral gamma delta T cell equilibrium via tumor-derived exosomes 29
CPT1A-mediated fatty acid oxidation promotes colorectal cancer cell metastasis by inhibiting anoikis 28
Estrogen receptor beta promotes renal cell carcinoma progression via regulating LncRNA HOTAIR-miR-138/200c/204/217 associated CeRNA network 28
Hypoxia-induced exosomes contribute to a more aggressive and chemoresistant ovarian cancer phenotype: a novel mechanism linking STAT3/Rab proteins 28
The management of retinoblastoma 27
Upregulation of the long noncoding RNA FOXD2-AS1 promotes carcinogenesis by epigenetically silencing EphB3 through EZH2 and LSD and predicts poor prognosis in gastric cancer 27
Employing mesenchymal stem cells to support tumor-targeted delivery of extracellular vesicle (EV)-encapsulated microRNA-379 27
Cisplatin-induced immune modulation in ovarian cancer mouse models with distinct inflammation profiles 27
Circular RNA profile identifies circOSBPL10 as an oncogenic factor and prognostic marker in gastric cancer 27