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Landscape of Nucleic Acid Modifications Induced by Chemical Warfare Agent
Author: Li, Kexin; Li, Hongliang; Zhang, Yuanyuan; Chen, Jia; Wu, Jianfeng; Xu, Hua; Xue, Jinjuan; Liu, Yulong; Guo, Lei; Xie, Jianwei
Journal: CHEMICAL RESEARCH IN TOXICOLOGY. 2026; Vol. 39, Issue 4, pp. 476-498. DOI: 10.1021/acs.chemrestox.6c00124
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Silver Nanoparticles Induce TET-Dependent Genome-Wide DNA Hydroxymethylation Alterations in Mouse Embryonic Stem Cells via Reactive Oxygen Species Signalin
Author: Chen, Shaokun; Yin, Junfa; Lai, Weiyi; Wang, Hailin
Journal: CHEMICAL RESEARCH IN TOXICOLOGY. 2026; Vol. 39, Issue 4, pp. 499-503. DOI: 10.1021/acs.chemrestox.6c00061
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Binding of N-(1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine Quinone (6PPDQ) to Mitochondrial Proteins Provokes Mitochondria Dysfunctio
Author: Wei, Naijie; Yan, Xiaowen; Yu, Mingyue; Li, Rong; Xiao, Zhixin; Chen, Shi; Yang, Limin; Wang, Qiuquan; Liu, Qian; Jiang, Guibin
Journal: CHEMICAL RESEARCH IN TOXICOLOGY. 2026; Vol. 39, Issue 3, pp. 283-292. DOI: 10.1021/acs.chemrestox.5c00250
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Inhibition of Four Anaplastic Lymphoma Kinase Inhibitors on the Activity of Human UDP-Glucuronosyltransferases and Prediction of Drug-Drug Interaction
Author: Yin, Hang; Wang, Xiaoyu; Wang, Zhe; Wang, Zhen; Lv, Xin; Jiang, Lili; Cao, Jun; Liu, Yong
Journal: CHEMICAL RESEARCH IN TOXICOLOGY. 2026; Vol. 39, Issue 3, pp. 417-426. DOI: 10.1021/acs.chemrestox.6c00032
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Mechanism-Based Inactivation of CYP2C19 by Anwuligan Resulting in Changes in Pharmacokinetic Properties of Amitriptylin
Author: Cheng, Xueqian; Cheng, Zihao; Dai, Jie; Yang, Dandan; Zhang, Qing; Tang, Hong; Peng, Ying; Li, Weiwei; Zheng, Jiang
Journal: CHEMICAL RESEARCH IN TOXICOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1021/acs.chemrestox.5c00392
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Endocrine Disruptor 2,7-Dibromocarbazole Disrupts Energy Metabolism and Alters Locomotor Behavior in Juvenile Zebrafis
Author: Zhou, Wendong; Shi, Lanxin; Yang, Jiawen; Yang, Zhimin; Cheng, Ziyan; Zhang, Mengye; Liu, Chang; Zhao, Nan; Ji, Chenyang; Zhao, Meirong; Song, Yang
Journal: CHEMICAL RESEARCH IN TOXICOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1021/acs.chemrestox.5c00494
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Mitochondrial DNA Damage Induced by Aristolochic Acid I: Recognizing the Heart as a Target Orga
Author: Kwok, Hong-Ching; Cheng, King-Hei; Chan, Wan
Journal: CHEMICAL RESEARCH IN TOXICOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1021/acs.chemrestox.6c00060
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Cytochrome P4501A1-Catalyzed Regioselective Activation Mechanism of PAHs and Their Nitrogen-Containing Derivative
Author: Hou, Zexi; Tong, Chenyang; Zheng, Mingna; Zhang, Weixin; Zhang, Qingzhu; Wang, Wenxing; Li, Yanwei
Journal: CHEMICAL RESEARCH IN TOXICOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1021/acs.chemrestox.5c00508
