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A model-based prion vaccine protects a transgenic mouse line carrying a Gerstmann-Sträussler-Scheinker disease mutatio
Author: Fang, Andrew; Tang, Xinli; Fleming, Madeleine; Tancowny, Brian; Wang, Xiongyao; Wang, YongLiang; Daude, Nathalie; Dorosh, Lyudmyla; Fleck, Shelaine C.; Rathod, Vineet; Coustou, Virginie; Cervantes, Silvia A.; Velasquez, Camilo Duque; Westaway, David; Aiken, Judd; McKenzie, Debbie; Telling, Glenn; Stepanova, Maria; Saupe, Sven J.; Siemer, Ansgar B.; Wille, Holger
Journal: ACTA NEUROPATHOLOGICA. 2026; Vol. 151, Issue 1, pp. -. DOI: 10.1007/s00401-026-03015-4
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Consensus statement on microglial and macrophage functions in glioma
Author: Zheng, Yuqi; Alzoubi, Islam; Graeber, Manuel B.; Anand, Atul; Barazzuol, Lara; Dorostkar, Mario; Frontzek, Karl; Golebiewska, Anna; Hadjipanayis, Costas G.; Hortobagyi, Tibor; Ismail, Azzam; Jansen, Gerard H.; Kaminska, Bozena; Kirschenbaum, Daniel; Komohara, Yoshihiro; Kristensen, Bjarne Winther; Lee, Kevin S.; Le Rhun, Emilie; Lu, Q. Richard; Matiasek, Kaspar; Mawrin, Christian; Michelucci, Alessandro; Montemurro, Nicola; Mouthon, Marc-André; Liu, Quan; Reimann, Regina; Sankowski, Roman; Schcolnik-Cabrera, Alejandro; Schulz, Michael; Schürch, Christian M.; Schwabenland, Marius; Tchoghandjian, Aurélie; Valiulytė-Simaitė, Indrė; Viapiano, Mariano S.; Weiss, Tobias; Weller, Michael; Wintermark, Max
Journal: ACTA NEUROPATHOLOGICA. 2026; Vol. 151, Issue 1, pp. -. DOI: 10.1007/s00401-026-02999-3
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Alzheimer's disease risk protein SorLA regulates ER homeostasis and lipid metabolism in human microglia, with conserved effects in neuron
Author: Haq, Imdadul; Ngo, Jason C.; Roy, Nainika; Lee, Emily; Choudhury, Muniyat A.; Soni, Rajesh K.; Teich, Andrew F.; Mayeux, Richard P.; De Jager, Philip L.; He, Ye; Wu, Xuebing; Bennett, David A.; Olah, Marta; Sher, Falak
Journal: ACTA NEUROPATHOLOGICA. 2026; Vol. 151, Issue 1, pp. -. DOI: 10.1007/s00401-026-03002-9
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Aberrant SOD1 aggregates in skeletal muscle target fibers in amyotrophic lateral sclerosi
Author: Li, Jieyu; Gao, Chao; Wang, Qingqing; Liu, Jing; Xie, Zhiying; Zhao, Yawen; Yu, Meng; Zheng, Yiming; Lv, He; Zhang, Wei; Yuan, Yun; Meng, Lingchao; Deng, Jianwen; Wang, Zhaoxia
Journal: ACTA NEUROPATHOLOGICA. 2026; Vol. 151, Issue 1, pp. -. DOI: 10.1007/s00401-026-03004-7
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α-synuclein triggers NCOA4-FTH1-mediated ferroptosis of oligodendrocyte in multiple system atroph
Author: Yu, Zhenwei; Arkin, Ehsan; Li, Yang; Canron, Marie-Helene; Arotcarena, Marie-Laure; Jadot, Hugo; Balpe, Elio; Huang, Yue; Feng, Tao; Meissner, Wassilios G.; Zhang, Jing
Journal: ACTA NEUROPATHOLOGICA. 2026; Vol. 151, Issue 1, pp. -. DOI: 10.1007/s00401-026-02978-8
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Spatially resolved molecular signatures of Lewy body dementi
Author: Jin, Yunjung; Chen, Kai; Wixom, Alexander Q.; Li, Zonghua; Koga, Shunsuke; Sekiya, Hiroaki; Xhafkollari, Gisela; Castanedes-Casey, Monica; Santhakumar, Hannah; Meneses, Axel D.; Neff, Abigail J.; Bu, Guojun; Heckman, Michael G.; Liu, Yuanhang; Ross, Owen A.; Dickson, Dennis W.; Zhao, Na
Journal: ACTA NEUROPATHOLOGICA. 2026; Vol. 151, Issue 1, pp. -. DOI: 10.1007/s00401-026-02981-z
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Pathological insights into cerebral amyloid angiopathy underlying intracerebral haemorrhage: population-based autopsy stud
Author: Su, Ya; Rodrigues, Mark A.; Samarasekera, Neshika; Loan, James J. M.; Hosking, Alice; Moullaali, Tom J.; Humphreys, Catherine A.; Mcdade, Karina; Millar, Tracey; Wardlaw, Joanna M.; Cheng, Xin; Van Veluw, Susanne J.; Al-Shahi Salman, Rustam; Smith, Colin
Journal: ACTA NEUROPATHOLOGICA. 2026; Vol. 151, Issue 1, pp. -. DOI: 10.1007/s00401-026-02980-0
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Biochemical signatures of skin α-synuclein in synucleinopathies revealed by RT-QuIC assay end-product analysi
Author: Gerasimenko, Maria; Yi, Hancun; Gilliland, Tricia; Chen, Yijia; Wang, Zerui; Zou, Wen-Quan
Journal: ACTA NEUROPATHOLOGICA. 2026; Vol. 151, Issue 1, pp. -. DOI: 10.1007/s00401-025-02973-5