Acta Neuropathologica

Acta Neuropathologica

神经病理学学报

  • 1区 中科院分区
  • Q1 JCR分区

高引用文章

文章名称 引用次数
Functional morphology of the blood-brain barrier in health and disease 81
Current state of Alzheimer's fluid biomarkers 76
Alzheimer's disease pathology propagation by exosomes containing toxic amyloid-beta oligomers 70
The role of brain barriers in fluid movement in the CNS: is there a 'glymphatic' system? 60
Molecular anatomy and functions of the choroidal blood-cerebrospinal fluid barrier in health and disease 52
Novel, improved grading system(s) for IDH-mutant astrocytic gliomas 50
Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold 42
Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas 40
Convective influx/glymphatic system: tracers injected into the CSF enter and leave the brain along separate periarterial basement membrane pathways 40
Aggregated Tau activates NLRP3-ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo 39
Novel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer's disease 37
Post-stroke inflammation-target or tool for therapy? 37
Inflammation in ALS/FTD pathogenesis 36
Progressive multiple sclerosis patients show substantial lesion activity that correlates with clinical disease severity and sex: a retrospective autopsy cohort analysis 34
Galectin- a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer's disease 32
Energy metabolism in ALS: an underappreciated opportunity? 31
Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes 31
Cerebrospinal fluid neurogranin concentration in neurodegeneration: relation to clinical phenotypes and neuropathology 31
Interplay among gut microbiota, intestinal mucosal barrier and enteric neuro-immune system: a common path to neurodegenerative diseases? 31
Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience 31
Aging alters the immunological response to ischemic stroke 30
Questions concerning the role of amyloid-beta in the definition, aetiology and diagnosis of Alzheimer's disease 30
The contribution of astrocytes to the neuroinflammatory response in multiple sclerosis and experimental autoimmune encephalomyelitis 29
Evidence for bidirectional and trans-synaptic parasympathetic and sympathetic propagation of alpha-synuclein in rats 27
Rapid lymphatic efflux limits cerebrospinal fluid flow to the brain 27
Does Parkinson's disease start in the gut? 27
The complexity of neuroinflammation consequent to traumatic brain injury: from research evidence to potential treatments 26
Glia-to-neuron transfer of miRNAs via extracellular vesicles: a new mechanism underlying inflammation-induced synaptic alterations 25
Tau seeding activity begins in the transentorhinal/entorhinal regions and anticipates phospho-tau pathology in Alzheimer's disease and PART 25
Mechanical disruption of the blood-brain barrier following experimental concussion 25
Molecularly defined diffuse leptomeningeal glioneuronal tumor (DLGNT) comprises two subgroups with distinct clinical and genetic features 24
Dissecting the genetic basis of focal cortical dysplasia: a large cohort study 24
FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy 24
Spread of aggregates after olfactory bulb injection of alpha-synuclein fibrils is associated with early neuronal loss and is reduced long term 24
Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations 24
A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity 24
The new genetic landscape of Alzheimer's disease: from amyloid cascade to genetically driven synaptic failure hypothesis? 24
Sense-encoded poly-GR dipeptide repeat proteins correlate to neurodegeneration and uniquely co-localize with TDP-43 in dendrites of repeat-expanded C9orf72 amyotrophic lateral sclerosis 24
MicroRNA-132 provides neuroprotection for tauopathies via multiple signaling pathways 24
Targeting pericytes for therapeutic approaches to neurological disorders 24
Distribution of EGFR amplification, combined chromosome 7 gain and chromosome 10 loss, and TERT promoter mutation in brain tumors and their potential for the reclassification of IDHwt astrocytoma to glioblastoma 23
Epitope determines efficacy of therapeutic anti-Tau antibodies in a functional assay with human Alzheimer Tau 23
The meninges as barriers and facilitators for the movement of fluid, cells and pathogens related to the rodent and human CNS 23
LRRK2 modifies alpha-syn pathology and spread in mouse models and human neurons 23
Detrimental and protective action of microglial extracellular vesicles on myelin lesions: astrocyte involvement in remyelination failure 22
Differential alpha-synuclein expression contributes to selective vulnerability of hippocampal neuron subpopulations to fibril-induced toxicity 22
Loss of histone H3K27me3 identifies a subset of meningiomas with increased risk of recurrence 22
Microglial cell loss after ischemic stroke favors brain neutrophil accumulation 22
Alpha-synuclein delays mitophagy and targeting Miro rescues neuron loss in Parkinson's models 21
Depopulation of dense alpha-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson's disease model 21