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Senescent Factors Suppress Innate Antiviral Immunity in Aged Mice via Two Distinct Mechanism
Author: Zhang, Xu; Zhang, Qi; Wang, Li; Li, Shu; Shu, Hong-Bing
Journal: AGING CELL. 2026; Vol. 25, Issue 4, pp. -. DOI: 10.1111/acel.70471
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RUVBL2 Regulates Microglia Metabolic Reprogramming to Mediate Stress Granules Aggregation Exacerbating Postoperative Delirium in Aged Mild Cognitive Impairment Rat
Author: Zhang, Lin; Wang, Zixuan; Yang, Chenyi; Wang, Xinyi; Liu, Xing; Zhang, Haonan; Liu, Huan; Liao, Huihui; Chen, Jun; Wang, Haiyun
Journal: AGING CELL. 2026; Vol. 25, Issue 4, pp. -. DOI: 10.1111/acel.70458
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Double-Pronged NAD Preservation: Delaying Cellular Senescence and Initiating Musculoskeletal Regeneratio
Author: Yu, Jianfeng; Hou, Mingzhuang; Deng, Yaoge; Yu, Chenqi; Liu, Yang; Kang, Kang; Xia, Xiaowei; Li, Xiaoping; Yang, Huilin; Jiang, Dinghua; Xu, Wu; Zhang, Yijian; Zhu, Xuesong
Journal: AGING CELL. 2026; Vol. 25, Issue 4, pp. -. DOI: 10.1111/acel.70468
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FGF21-Mediated Upregulation of SIRT1 Delays Intervertebral Disc Degeneration by Promoting PINK1/Parkin Dependent Mitophagy Through Deacetylation of FOXO
Author: Wu, Zuo-long; Ran, Rui; Xie, Qi-qi; Zhang, Cong; Chen, Ya-jun; Cheng, Peng; Wang, Ke-Ping; Zhang, Hai-hong
Journal: AGING CELL. 2026; Vol. 25, Issue 4, pp. -. DOI: 10.1111/acel.70449
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MicroRNA-128-3p Deficiency Alleviates Bone Loss in Age-Related Osteoporosis via Activation of Canonical Wnt Signalin
Author: Shen, Gengyang; Chen, Kun; Shang, Qi; Chen, Honglin; Liu, Yu; Chen, Guifeng; Qin, Weicheng; He, Jiahui; Zhang, Yuzhuo; Zhao, Wenhua; Qiu, Weiyu; Zhang, Jingzhi; Ren, Hui; Jiang, Xiaobing
Journal: AGING CELL. 2026; Vol. 25, Issue 4, pp. -. DOI: 10.1111/acel.70460
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Single-Cell Profiling Reveals Distinct Immune Communication Networks in Centenarians and Elderly Control
Author: Qiu, Liwei; Dong, Chen; Zhao, Rui; Ye, Huiyuan; Gao, Jian-lin; Chen, Yizhi; Sun, Chi; Gu, Zhifeng
Journal: AGING CELL. 2026; Vol. 25, Issue 4, pp. -. DOI: 10.1111/acel.70486
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Senescence-Driven IL-17A Inflammatory Circuit Promotes Epithelial-Mesenchymal Transition (EMT) and Progression in Age-Related Posterior Subcapsular Cataract
Author: Ni, Yan; Ma, Yu; Ren, Zewen; Zhu, Yi; Liu, Liangping; Duan, Runping; Qin, Lu; Chen, Yang; Ju, Rong; Qin, Yingyan; Wu, Mingxing
Journal: AGING CELL. 2026; Vol. 25, Issue 4, pp. -. DOI: 10.1111/acel.70456
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Physical Fitness Is Negatively Associated With DNA Methylation-Based Risk of Aging-Related Disease
Author: Nasser, Samiha; Keringer, Johanna; Gu, Yaodong; Boldogh, Istvan; Ba, Xueqing; Higuchi, Mitsuru; Kerepesi, Csaba; Radak, Zsolt
Journal: AGING CELL. 2026; Vol. 25, Issue 4, pp. -. DOI: 10.1111/acel.70467
