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Microbial-derived 3-phenylpropionic acid orchestrates immune-progenitor cell crosstalk to promote beige adipogenesis and energy expenditur
Author: Li, Defu; Xia, Bo; Hu, Ruoci; Zhang, Zhao; Xu, Cong; Zhou, Hanjian; Li, Xiao; Hua, Yonglin; Wu, Shusong; Zhang, Ke; Jiang, Yuwei; Wu, Jiangwei; Yuan, Yexian
Journal: CELL METABOLISM. 2026; Vol. 38, Issue 4, pp. 763-778. DOI: 10.1016/j.cmet.2026.01.017
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Neuroimmunometabolic co-evolution in the tumor micro-and macroenvironmen
Author: Zhang, Yu; Zhuang, Weijie; Zhu, Haodong; Meng, Fansheng; Chen, Mingtao; Guo, Yibo; Fan, Jia; Sun, Yunfan; Ji, Tong
Journal: CELL METABOLISM. 2026; Vol. 38, Issue 4, pp. 655-672. DOI: 10.1016/j.cmet.2026.02.001
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Vitamin C slows primate aging by targeting iron-driven lipid peroxidatio
Author: Yu, Pei-Long; Xu, Cheng-Ran
Journal: CELL METABOLISM. 2026; Vol. 38, Issue 4, pp. 635-637. DOI: 10.1016/j.cmet.2026.02.011
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Lipid-induced granules in hepatocytes alleviate liver fibrosi
Author: Li, Yunhui; Lei, Ting; Nie, Wen; Ma, Mingrui; Zhao, Wei; Zhou, Ye; Liu, Yanfang; Wang, Minjun; Jia, Kaiwei; Liu, Shanrong; Wang, Yuanyuan; Fan, Yiwen; Chen, Long; He, Xing; Yuan, Jihang; Cao, Xuetao; Hou, Jin
Journal: CELL METABOLISM. 2026; Vol. 38, Issue 4, pp. 746-762. DOI: 10.1016/j.cmet.2025.12.015
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Compartmentalized branched-chain amino acid metabolism orchestrates colorectal cancer dissemination via an UMP-vimentin axi
Author: Ji, Fenfen; Huang, Pingmei; Zhou, Qiming; Ko, Lok Hin; Wei, Qinyao; Chan, Charis Cheuk-Lok; Chen, Danyu; Chen, Huarong; Kang, Wei; Cheung, Alvin Ho-Kwan; Cheng, Cillian H.; Shen, Jianming; Pan, Yasi; Jiao, Ying; Zhu, Lin; Chik, Tat Wai; Xie, Peisi; Liang, Xiao; Kranenburg, Onno; Cai, Zongwei; Yu, Jun; Wong, Chi Chun
Journal: CELL METABOLISM. 2026; Vol. 38, Issue 4, pp. 794-811. DOI: 10.1016/j.cmet.2026.01.007
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Uridine depletion impairs CD8+T cell antitumor activity through N-glycosylatio
Author: Xiao, Jianbiao; Li, Zhiyang; Ding, Yi; Zhu, Kejin; Zheng, Zhihao; Zhang, Yaowei; Weng, Jiawen; Wang, Feifei; Zhang, Yuqin; Zeng, Sisi; Qiu, Minxing; Zhang, Zhaowen; Wang, Zhizhang; Liang, Li
Journal: CELL METABOLISM. 2026; Vol. 38, Issue 3, pp. -. DOI: 10.1016/j.cmet.2025.11.016
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Microbial metabolite FAD mobilizes adipocyte lipid remodeling to enhance cancer immunotherapy efficac
Author: Tong, Tianying; Huang, Xiaowen; Li, Lingxi; Hu, Muni; Zhu, Xiaoqiang; Zhu, Beiyao; Ma, Yanru; Ning, Lijun; Jiang, Yi; Zhang, Yue; Zhou, Yilu; Wang, Zhenyu; Ding, Jinmei; Zhao, Ying; Xuan, Baoqin; Zhang, Youwei; Xiao, Xiuying; Fang, Jing-Yuan; Hong, Jie; Yin, Yan; Liu, Fenglin; Chen, Haoyan
Journal: CELL METABOLISM. 2026; Vol. 38, Issue 3, pp. -. DOI: 10.1016/j.cmet.2025.12.012
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Semaglutide ameliorates osteoarthritis progression through a weight loss-independent metabolic restoration mechanis
Author: Qin, Hongyu; Yu, Jiamin; Yu, Huan; Zhu, Chuqiao; Yuan, Dongfeng; Wang, Ziling; Zhu, Zhenglin; Wei, Guizheng; Ou, Peiyan; Li, Zhibin; Jiang, Hua; Shen, Jie; Xiao, Guozhi; Bai, Xiaochun; Wang, Huaiyu; Zhang, Huan-Tian; Speakman, John R.; Chen, Di; Tong, Liping
Journal: CELL METABOLISM. 2026; Vol. 38, Issue 3, pp. -. DOI: 10.1016/j.cmet.2026.01.008
