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The poly-(HA-GMA) hydrogel carrying AAV8-sTβRII alleviates scar formation in mice skin wound healing by inhibiting fibrosi
Author: Chen, Jinhao; Zhan, Lijun; Duan, Jinyan; Wang, Tianning; Meng, Zenan; Wang, Qianru; Yang, Jianlin; Huang, Xiaofei; Liao, Yue; Song, Xinyu; Cao, Chunyu
Journal: GENE THERAPY. 2026; Vol. , Issue , pp. -. DOI: 10.1038/s41434-026-00608-2
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Ultrasound-guided left heart injection: a safer and more efficient strategy for mouse thoracic aortic gene deliver
Author: Yang, Yanmiao; Xu, Kunyao; Yuan, Ya; Huang, Bo; Wei, Shan; Zhao, Yi; Song, Yang; Liu, Daxing; Liu, Jianguo; Zhang, Dengshen
Journal: GENE THERAPY. 2026; Vol. , Issue , pp. -. DOI: 10.1038/s41434-026-00603-7
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Preclinical evaluation of lentiviral gene therapy for adenosine deaminase 2 deficiency (DADA2): engraftment efficiency and biodistribution in humanised NBSGW mic
Author: Hong, Ying; Burleigh, Alice; Liao, Aiyin; Yeung, Jenny; Bian, Yixin; Sebire, Neil; Ogunbiyi, Olumide; Omoyinmi, Ebun; Thrasher, Adrian J.; Morris, Emma; Brogan, Paul A.; Eleftheriou, Despina
Journal: GENE THERAPY. 2025; Vol. , Issue , pp. -. DOI: 10.1038/s41434-025-00547-4
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Recombinant oncolytic virus NDV-anti-VEGFR2 enhances radiotherapy sensitivity in NSCLC by targeting VEGF signaling and impairing DNA repai
Author: Liu, Liang; Song, Liying; Liu, Tianyan; Hui, Kaiyuan; Hu, Chenxi; Yang, Jiarui; Pi, Xuelei; Yan, Yuanyuan; Liu, Shishi; Zhang, Yating; Chen, Hongna; Cao, Yukai; Zhou, Lihua; Qiao, Yun; Yu, Dan; Yin, Chengkai; Li, Xu; Zhang, Chenfeng; Li, Deshan; Wang, Zhenzhong; Liu, Zhihang; Jiang, Xiaodong
Journal: GENE THERAPY. 2025; Vol. , Issue , pp. -. DOI: 10.1038/s41434-025-00540-x
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RNAi targeting heparin cofactor II promotes hemostasis in a canine model of acquired hemophilia
Author: Zhang, Yuyang; Liu, Tingting; Kou, Haiming; Wang, Huafang; Hu, Yu; Tang, Liang V
Journal: GENE THERAPY. 2025; Vol. , Issue , pp. -. DOI: 10.1038/s41434-025-00541-w
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Expression of anti-amyloid CARs in microglia promotes efficient and selective phagocytosis of Aβ1-4
Author: Heiss, Christina N.; Riise, Rebecca; Hanse, Eric; Fruhwurth, Stefanie; Zetterberg, Henrik; Bjorefeldt, Andreas
Journal: GENE THERAPY. 2025; Vol. , Issue , pp. -. DOI: 10.1038/s41434-025-00534-9
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A peptide conjugate enables systemic injection of the morpholino inducer and more durable induction of T3H38 ribozyme-controlled AAV transgene in mic
Author: Tang, Xiaojuan; Wang, Haimin; Yin, Yandong; Zhong, Guocai
Journal: GENE THERAPY. 2025; Vol. , Issue , pp. -. DOI: 10.1038/s41434-025-00519-8
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Safety, efficacy, and immunogenicity of a novel IgG degrading enzyme (KJ103): results from two randomised, blinded, phase 1 clinical trial
Author: Cao, Mengdie; Katial, Rohit; Liu, Yanjun; Lu, Xiaoyu; Gu, Qin; Chen, Chen; Liu, Katie; Zhu, Zhen; Marshall, Mark R.; Yu, Yanxia; Wang, Zheng
Journal: GENE THERAPY. 2025; Vol. , Issue , pp. -. DOI: 10.1038/s41434-025-00512-1
