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E3 ubiquitin ligase SMURF2 prevents colorectal cancer by reducing the stability of the YY1 protein and inhibiting the SENP1/c-myc axis
Author: Gao, Qianfu; Wang, Shanchao; Zhang, Zeyan
Journal: GENE THERAPY. 2023; Vol. 30, Issue 1-2, pp. 51-63. DOI: 10.1038/s41434-021-00289-z
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Oncolytic Newcastle disease virus expressing the co-stimulator OX40L as immunopotentiator for colorectal cancer therapy
Author: Tian, Limin; Liu, Tianyan; Jiang, Shan; Cao, Yukai; Kang, Kai; Su, Han; Ren, Guiping; Wang, Zhenzhong; Xiao, Wei; Li, Deshan
Journal: GENE THERAPY. 2023; Vol. 30, Issue 1-2, pp. 64-74. DOI: 10.1038/s41434-021-00256-8
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Overexpressed ski efficiently promotes neurorestoration, increases neuronal regeneration, and reduces astrogliosis after traumatic brain injury
Author: Zhai, Yu; Ye, Shi-Yang; Wang, Qiu-Shi; Xiong, Ren-Ping; Fu, Sheng-Yu; Du, Hao; Xu, Ya-Wei; Peng, Yan; Huang, Zhi-Zhong; Yang, Nan; Zhao, Yan; Ning, Ya-Lei; Li, Ping; Zhou, Yuan-Guo
Journal: GENE THERAPY. 2023; Vol. 30, Issue 1-2, pp. 75-87. DOI: 10.1038/s41434-022-00320-x
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Effect of nanoparticle-mediated delivery of SFRP4 siRNA for treating Dupuytren disease
Author: Jin, Rujue; Zhu, Weigang; Xu, Jiajun; Gu, Jianhui; Deng, Aidong
Journal: GENE THERAPY. 2023; Vol. 30, Issue 1-2, pp. 31-40. DOI: 10.1038/s41434-022-00330-9
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Exosomal PD-L1 confers chemoresistance and promotes tumorigenic properties in esophageal cancer cells via upregulating STAT3/miR-21
Author: Wang, Haojie; Qi, Yijun; Lan, Zijun; Liu, Qiwei; Xu, Juanjuan; Zhu, Mengxi; Yang, Tingting; Shi, Ruolin; Gao, Shegan; Liang, Gaofeng
Journal: GENE THERAPY. 2023; Vol. 30, Issue 1-2, pp. 88-100. DOI: 10.1038/s41434-022-00331-8
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Forced activation of dystrophin transcription by CRISPR/dCas9 reduced arrhythmia susceptibility via restoring membrane Nav1.5 distribution
Author: Zhang, Ruixin; Liu, Junwu; Xue, Genlong; Yang, Jiming; Li, Desheng; Tian, Tao; Zhang, Xiaofang; Gao, Kangyi; Pan, Zhenwei
Journal: GENE THERAPY. 2023; Vol. 30, Issue 1-2, pp. 142-149. DOI: 10.1038/s41434-022-00348-z
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Identification of RPGR ORF15 mutation for X-linked retinitis pigmentosa in a large Chinese family and in vitro correction with prime editor
Author: Lv, Xiujuan; Zheng, Zheng; Zhi, Xiao; Zhou, Yilin; Lv, Jineng; Zhou, Yue; Wu, Binrong; Liu, Sixiu; Shi, Wei; Song, Zongming; Xu, Jinling; Qu, Jia; Xu, Dan; Gu, Feng
Journal: GENE THERAPY. 2023; Vol. 30, Issue 1-2, pp. 160-166. DOI: 10.1038/s41434-022-00352-3
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Intracerebral lentiviral ABCD1 gene therapy in an early disease onset ALD mouse model
Author: Gong, Jie; Liu, Yunyun; Chung, Tsai-Hua; Xu, Liu; Lund, Troy C.; Chang, Lung-Ji
Journal: GENE THERAPY. 2023; Vol. 30, Issue 1-2, pp. 18-30. DOI: 10.1038/s41434-022-00355-0