| Understanding the molecular biology of intervertebral disc degeneration and potential gene therapy strategies for regeneration: a review |
22 |
| LncRNA FTX sponges miR-215 and inhibits phosphorylation of vimentin for promoting colorectal cancer progression |
19 |
| Long noncoding RNA Meg3 regulates cardiomyocyte apoptosis in myocardial infarction |
19 |
| Optimization of lentiviral vector production for scale-up in fixed-bed bioreactor |
18 |
| Inside out: optimization of lipid nanoparticle formulations for exterior complexation and in vivo delivery of saRNA |
15 |
| Inhibition of microRNA-495 suppresses chondrocyte apoptosis through activation of the NF-kappa B signaling pathway by regulating CCL4 in osteoarthritis |
13 |
| Targeted in vivo knock-in of human alpha-1-antitrypsin cDNA using adenoviral delivery of CRISPR/Cas9 |
13 |
| Beyond cystic fibrosis transmembrane conductance regulator therapy: a perspective on gene therapy and small molecule treatment for cystic fibrosis |
12 |
| Improved therapeutic potential of MSCs by genetic modification |
12 |
| AAV-mediated NT-3 overexpression protects cochleae against noise-induced synaptopathy |
11 |
| Astrocyte-selective AAV gene therapy through the endogenous GFAP promoter results in robust transduction in the rat spinal cord following injury |
9 |
| Serotype survey of AAV gene delivery via subconjunctival injection in mice |
9 |
| Nanosphere-mediated co-delivery of VEGF-A and PDGF-B genes for accelerating diabetic foot ulcers healing in rats |
9 |
| Characterization of abscopal effects of intratumoral electroporation-mediated IL-12 gene therapy |
8 |
| A next-generation sequencing method for gene doping detection that distinguishes low levels of plasmid DNA against a background of genomic DNA |
8 |
| Rationally designed AAV2 and AAVrh8R capsids provide improved transduction in the retina and brain |
7 |
| Effect of PAK1 gene silencing on proliferation and apoptosis in hepatocellular carcinoma cell lines MHCC97-H and HepG2 and cells in xenograft tumor |
7 |
| Feasibility of using NF1-GRD and AAV for gene replacement therapy in NF1-associated tumors |
6 |
| GDNF-mediated rescue of the nigrostriatal system depends on the degree of degeneration |
6 |
| HIV infection alters the human epigenetic landscape |
6 |
| Downreguation of FoxM1 by miR-214 inhibits proliferation and migration in hepatocellular carcinoma |
6 |
| More expansive gene transfer to the rat CNS: AAV PHP.EB vector dose-response and comparison to AAV PHP.B |
5 |
| Superior human hepatocyte transduction with adeno-associated virus vector serotype 7 |
5 |
| Immunosuppression overcomes insulin- and vector-specific immune responses that limit efficacy of AAV2/8-mediated insulin gene therapy in NOD mice |
5 |
| Scaffold-mediated delivery for non-viral mRNA vaccines |
5 |
| MR-guided delivery of AAV2-BDNF into the entorhinal cortex of non-human primates |
5 |
| CCAT1 stimulation of the symmetric division of NSCLC stem cells through activation of the Wnt signalling cascade |
5 |
| AAV-encoded Ca(V)2.2 peptide aptamer CBD3A6K for primary sensory neuron-targeted treatment of established neuropathic pain |
5 |
| Ectopic BAT mUCP-1 overexpression in SKM by delivering a BMP7/PRDM16/PGC-1a gene cocktail or single PRMD16 using non-viral UTMD gene therapy |
4 |
| Characterization of neural stem cells modified with hypoxia/neuron-specific VEGF expression system for spinal cord injury |
4 |
| AAVrh-10 transduces outer retinal cells in rodents and rabbits following intravitreal administration |
4 |
| Polarized AAVR expression determines infectivity by AAV gene therapy vectors |
4 |
| Anti-angiogenic treatment of endometriosis via anti-VEGFA siRNA delivery by means of peptide-based carrier in a rat subcutaneous model |
4 |
| Widespread transduction of astrocytes and neurons in the mouse central nervous system after systemic delivery of a self-complementary AAV-PHP.B vector |
4 |
| Improving therapeutic efficacy of IL-12 intratumoral gene electrotransfer through novel plasmid design and modified parameters |
4 |
| AAV1.NT-3 gene therapy increases muscle fiber diameter through activation of mTOR pathway and metabolic remodeling in a CMT mouse model |
4 |
| ILK promotes survival and self-renewal of hypoxic MSCs via the activation of lncTCF7-Wnt pathway induced by IL-6/STAT3 signaling |
4 |
| Effects of microRNA-292-5p on myocardial ischemia-reperfusion injury through the peroxisome proliferator-activated receptor-alpha/-gamma signaling pathway |
4 |
| Retina transduction by rAAV2 after intravitreal injection: comparison between mouse and rat |
4 |
| MiR-21 derived from the exosomes of MSCs regulates the death and differentiation of neurons in patients with spinal cord injury |
3 |
| Evaluation of the Glypican 3 promoter for transcriptional targeting of hepatocellular carcinoma |
3 |
| Primary T cells for mRNA-mediated immunotoxin delivery |
3 |
| Dual-targeted NIS polyplexes-a theranostic strategy toward tumors with heterogeneous receptor expression |
3 |
| Factors governing the transduction efficiency of adeno-associated virus in the retinal ganglion cells following intravitreal injection |
3 |
| Optimization of viral protein ratios for production of rAAV serotype 5 in the baculovirus system |
3 |
| Bat adeno-associated viruses as gene therapy vectors with the potential to evade human neutralizing antibodies |
3 |
| Safety and efficacy evaluations of an adeno-associated virus variant for preparing IL10-secreting human neural stem cell-based therapeutics |
3 |
| In vitro evaluation of a lentiviral two-step transcriptional amplification system using GAL4FF transactivator for gene therapy applications in bone repair |
3 |
| AAV9 Vector: a Novel modality in gene therapy for spinal muscular atrophy |
3 |
| Superior lentiviral vectors designed for BSL-0 environment abolish vector mobilization |
2 |
