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Alternatively activated monocyte-derived myeloid cells promote extracellular pathogen persistence in pulmonary fungal granuloma
Author: Zheng, Yufan; Jean Pierre, Makheni; Ansaldo, Eduard; Dobson, Hannah E.; Kamenyeva, Olena; Onyishi, Chinaemerem U.; Douglas, Sarah; Febres Aldana, Christopher; Engin Zerk, Pinar; Sereti, Irini; Betancourt, Jovany J.; Nielsen, Kirsten; McCaffery, Erin; Dang, Eric V
Journal: JOURNAL OF EXPERIMENTAL MEDICINE. 2026; Vol. 223, Issue 5, pp. -. DOI: 10.1084/jem.20260208
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Targeting Mettl8-Tcf1 axis promotes CD8+ TPEX differentiation and antitumor immunit
Author: Song, Jiaxi; Cui, Dan; Wang, Jiabao; Qi, Xuewei; Ma, Jiaxin; Liu, Qing; Yang, Jing; Yu, Haoyu; Ye, Lilin; Huang, Qizhao; Li, Jia; Li, Fengyin
Journal: JOURNAL OF EXPERIMENTAL MEDICINE. 2026; Vol. 223, Issue 5, pp. -. DOI: 10.1084/jem.20250424
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TIE2 links MEKK3-KLF2/4 and PI3K signaling in cerebral cavernous malformatio
Author: Li, Lun; Castro, Marco; Hongo, Hiroki; Ren, Jian; Shenkar, Robert; Jabarkheel, Rashad; Gao, Siqi; Narayan, Sweta; Frankfurter, Maxwell; Tang, Alan T.; Yang, Jisheng; Chen, Mei; Bockman, Jenna; Mericko-Ishizuka, Patricia; Alcazar, Roberto; Sader, Georgio; Iqbal, Javed; Kinkade, Serena; Lightle, Rhonda; Ressler, Andrew K.; Qu, Xianghu; Baldwin, H. Scott; Marchuk, Douglas A.; Awad, Issam A.; Burkhardt, Jan-Karl; Potente, Michael; Kahn, Mark L
Journal: JOURNAL OF EXPERIMENTAL MEDICINE. 2026; Vol. 223, Issue 5, pp. -. DOI: 10.1084/jem.20251374
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Basophils drive the resolution and promote wound healing in adult and aged mic
Author: Bex, Julie; Peter, Victoria; Saji, Chaimae; Dupont, Claire; Lavernhe, Mathilde; Jin, Suoqin; Chapart, Lea; Gautier, Gregory; Thibaudeau, Olivier; Thaminy, Morgane K.; Tchen, John; Simon, Quentin; Dai, Xing; Miyake, Kensuke; Karasuyama, Hajime; Jiang, Jean X.; Naidoo, Karmella; Benhamou, Marc; Blank, Ulrich; Monteiro, Renato C.; Le Gros, Graham; Coste, Agnes; Charles, Nicolas; Pellefigues, Christophe
Journal: JOURNAL OF EXPERIMENTAL MEDICINE. 2026; Vol. 223, Issue 5, pp. -. DOI: 10.1084/jem.20240764
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Hypoxia-inducible protein 2 mediates metabolic adaptation of Ly6ChighLy6Glow monocytes after strok
Author: Chen, Weijie; Wang, Xin; Huang, Tingting; Li, Yan; Chen, Chen; Zhang, Yueman; Xie, Wanqing; Tang, Dan; Fan, Qiuyue; Pang, Rui; Yin, Jiemin; Sparwasser, Tim; Wang, Zhenghong; Liesz, Arthur; Gan, Yu; Yu, Weifeng; Ginhoux, Florent; Li, Peiying
Journal: JOURNAL OF EXPERIMENTAL MEDICINE. 2026; Vol. 223, Issue 4, pp. -. DOI: 10.1084/jem.20242025
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Defects in intron recycling suppress the antiviral response via a mechanism of intronic endogenous dsRN
Author: Duan, Chaorui; Buerer, Luke; Bowers, Cory; Taggart, Allison J.; O'brien, Mara H.; Gunasekera, Sarah; Lin, Chien-Ling; Wang, Jing; Zeng, Yi; Staley, Jonathan P.; Fredericks, Alger M.; Monaghan, Sean F.; Welch, Anastasia; Clark, Nathaniel E.; Gao, Daxing; Marr, Nico; Zhang, Shen-Ying; Casanova, Jean-Laurent; Fairbrother, William G
Journal: JOURNAL OF EXPERIMENTAL MEDICINE. 2026; Vol. 223, Issue 4, pp. -. DOI: 10.1084/jem.20250344
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Zbtb32 promotes CD8+ T cell differentiation and function in cance
Author: Pan, Birui; Sun, Qinli; Li, Ruifeng; Feng, Juan; Hao, Jing; Xie, Bowen; Zhao, Xiaohong; Zhao, Zixuan; Wei, Peng; Lan, Qiuyan; Xie, Shiyuan; Xie, Tian; Chen, Yongzhen; Wei, Kun; Zhong, Xuan; Qi, Hai; Ni, Ling; Dong, Chen
Journal: JOURNAL OF EXPERIMENTAL MEDICINE. 2026; Vol. 223, Issue 4, pp. -. DOI: 10.1084/jem.20250005
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Epigenetic and metabolic reprogramming support plasma cell differentiation in germinal center
Author: Wang, Yuliang; Yang, Xinyi; Lou, Mengting; Chen, Tiantian; Li, Wen; Yang, Cuifang; Zhang, Le; Cai, Zhenming; Fan, Yuren; Zhai, Sulan; Zhang, Shengze; Wang, Yunli; Wang, Xiaoming; Chen, Jingjing
Journal: JOURNAL OF EXPERIMENTAL MEDICINE. 2026; Vol. 223, Issue 3, pp. -. DOI: 10.1084/jem.20250569
