Journal Of Experimental Medicine

Journal Of Experimental Medicine

实验医学杂志

  • 1区 中科院分区
  • Q1 JCR分区

高引用文章

文章名称 引用次数
The cGAS-cGAMP-STING pathway connects DNA damage to inflammation, senescence, and cancer 141
Context-dependent EMT programs in cancer metastasis 75
Growth of Mycobacterium tuberculosis in vivo segregates with host macrophage metabolism and ontogeny 69
The gut microbiome: Relationships with disease and opportunities for therapy 64
The immunology of hypertension 58
Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity 53
Peripherally derived macrophages can engraft the brain independent of irradiation and maintain an identity distinct from microglia 52
Tissue-resident macrophages in the intestine are long lived and defined by Tim-4 and CD4 expression 51
High-dimensional single cell analysis identifies stem-like cytotoxic CD8(+) T cells infiltrating human tumors 48
Bile acids in glucose metabolism in health and disease 47
IgA regulates the composition and metabolic function of gut microbiota by promoting symbiosis between bacteria 45
Neutrophils facilitate ovarian cancer premetastatic niche formation in the omentum 44
Cardiac macrophages promote diastolic dysfunction 43
Optimized RNP transfection for highly efficient CRISPR/Cas9-mediated gene knockout in primary T cells 42
Bone marrow-derived fibroblasts are a functionally distinct stromal cell population in breast cancer 42
Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model 41
4-1BB costimulation induces T cell mitochondrial function and biogenesis enabling cancer immunotherapeutic responses 41
Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy 40
Organ-specific lymphatic vasculature: From development to pathophysiology 39
Neutrophils instruct homeostatic and pathological states in naive tissues 39
Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses 33
Loss of the interleukin-6 receptor causes immunodeficiency, atopy, and abnormal inflammatory responses 33
TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation 33
Resolvins suppress tumor growth and enhance cancer therapy 32
Macrophages of distinct origins contribute to tumor development in the lung 32
TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading 31
GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever 31
Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non-small cell lung cancer 31
Deficiency in T follicular regulatory cells promotes autoimmunity 31
Development of immune checkpoint therapy for cancer 30
A major role for ferroptosis in Mycobacterium tuberculosis-induced cell death and tissue necrosis 29
Rapid activation of tumor-associated macrophages boosts preexisting tumor immunity 29
Specific targeting of CD163(+) TAMs mobilizes inflammatory monocytes and promotes T cell-mediated tumor regression 29
Microbiome-microglia connections via the gut-brain axis 29
A common transcriptomic program acquired in the thymus defines tissue residency of MAIT and NKT subsets 29
NK cells switch from granzyme B to death receptor-mediated cytotoxicity during serial killing 28
CSF-1 controls cerebellar microglia and is required for motor function and social interaction 28
ApoE facilitates the microglial response to amyloid plaque pathology 27
Immune cells and CNS physiology: Microglia and beyond 27
Type I interferons in tuberculosis: Foe and occasionally friend 27
Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism 27
Dysregulation of sphingolipid metabolism contributes to bortezomib-induced neuropathic pain 26
Antigen-presenting ILC3 regulate T cell-dependent IgA responses to colonic mucosal bacteria 26
Single-cell transcriptomic analysis of tissue-resident memory T cells in human lung cancer 26
Contextual control of skin immunity and inflammation by Corynebacterium 26
Sex-specific effects of microbiome perturbations on cerebral A beta amyloidosis and microglia phenotypes 26
CXCR6 regulates localization of tissue-resident memory CD8 T cells to the airways 26
Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation 25
ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING 25
Modulating inflammation for cancer therapy 24