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IPMK-1 governs C. elegans physiology through ceTOR but lifespan via a distinct IP3-dependent pathwa
Author: He, Xuan-Xuan; Huang, Qiong; Yu, Xin-Tian; Shi, Lin; Ou, Li-Lan; Wu, Gui-Sheng; Luo, Huai-Rong
Journal: MECHANISMS OF AGEING AND DEVELOPMENT. 2026; Vol. 231, Issue , pp. -. DOI: 10.1016/j.mad.2026.112179
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Inflammaging in geriatric liver disease: Mechanistic insights and therapeutic frontier
Author: Xu, Xu; Wei, Xiao; Yang, Xiaolin; Lin, Shaofang
Journal: MECHANISMS OF AGEING AND DEVELOPMENT. 2026; Vol. 231, Issue , pp. -. DOI: 10.1016/j.mad.2026.112165
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NAD plus as a central metabolic hub Regulating the hallmarks of aging: Mechanisms and therapeutic implication
Author: Pei, Zerong; Liang, Fengni; Wang, Xuemei; Li, Hui
Journal: MECHANISMS OF AGEING AND DEVELOPMENT. 2026; Vol. 231, Issue , pp. -. DOI: 10.1016/j.mad.2026.112174
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SRC suppression attenuates vascular aging by activating FUNDC1-dependent mitophag
Author: Wang, Linghuan; Ma, Yan; Wang, Tianhu; Zhang, Weiwei; Fang, Zhiyi; Lu, Tingting; Zhang, Yingjie; Fang, Yan; Sun, Ting; Han, Dong; Cao, Feng
Journal: MECHANISMS OF AGEING AND DEVELOPMENT. 2026; Vol. 230, Issue , pp. -. DOI: 10.1016/j.mad.2026.112156
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Senescent cancer-associated fibroblasts in cancer progression: From formation to therapeutic opportunitie
Author: Feng, Yingying; Zhi, Xiaochen; Xiao, Ting; Feng, Lin
Journal: MECHANISMS OF AGEING AND DEVELOPMENT. 2026; Vol. 230, Issue , pp. -. DOI: 10.1016/j.mad.2026.112158
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Inflammatory and genetic mechanisms mediate the association between frailty and incident atopic dermatitis in middle-aged and elderly adult
Author: Deng, Peizhi; Tang, Siyu; Zeng, Jinron; Lu, Jianyun
Journal: MECHANISMS OF AGEING AND DEVELOPMENT. 2026; Vol. 230, Issue , pp. -. DOI: 10.1016/j.mad.2025.112148
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Blood aging: From definition and mechanisms to clinical practic
Author: Yin, Qiliang; Zhang, Yan; Yi, Xingcheng; Li, Jian; Dai, Yun; Jin, Fengyan
Journal: MECHANISMS OF AGEING AND DEVELOPMENT. 2026; Vol. 229, Issue , pp. -. DOI: 10.1016/j.mad.2025.112144
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Apelin-13 activates TFEB-mediated autophagy via AMPK to attenuate senescence and pyroptosis in nucleus pulposus cells during intervertebral disc degeneratio
Author: Gong, Yuhang; Xiang, Jie; Wang, Ben; Hu, Leyi; Shao, Shengzan; Wu, Yangyang; Li, Ze; Jiang, Chao; Qiu, Jianxin; Ying, Liwei; Hong, Zhenghua; Chen, Haixiao; Wang, Zhangfu
Journal: MECHANISMS OF AGEING AND DEVELOPMENT. 2026; Vol. 229, Issue , pp. -. DOI: 10.1016/j.mad.2025.112147
