Mechanisms Of Ageing And Development

Mechanisms Of Ageing And Development

老龄化与发展机制

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  • Q1 JCR分区

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文章名称 引用次数
The impact of oxidative DNA damage and stress on telomere homeostasis 40
Stress, cell senescence and organismal ageing 40
DNA methylation dynamics in aging: how far are we from understanding the mechanisms? 27
Regulation of metabolic health by essential dietary amino acids 20
Is DNA damage indispensable for stress-induced senescence? 18
The role of TGF beta in wound healing pathologies 17
Mechanisms of aging and development-A new understanding of environmental damage to the skin and prevention with topical antioxidants 17
Review and meta-analysis of genetic polymorphisms associated with exceptional human longevity 17
The senescent bystander effect is caused by ROS-activated NF-kappa B signalling 16
Photoaging and skin cancer: Is the inflammasome the missing link? 16
Frailty biomarkers in humans and rodents: Current approaches and future advances 16
Keratinocytes oxidative damage mechanisms related to airbone particle matter exposure 15
Circular RNA involvement in aging: An emerging player with great potential 14
CircRNA accumulation: A new hallmark of aging? 14
Role of hypothalamus in aging and its underlying cellular mechanisms 14
The physiopathologic role of oxidative stress in skeletal muscle 14
Caloric restriction and cellular senescence 14
Age-related deficit accumulation and the diseases of ageing 13
Age-related evolutions of the dermis: Clinical signs, fibroblast and extracellular matrix dynamics 12
The epigenetic alterations of endogenous retroelements in aging 11
PIWI-piRNA pathway: Setting the pace of aging by reducing DNA damage 10
Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3 10
Tauopathy: A common mechanism for neurodegeneration and brain aging 10
Ferrosenescence: The iron age of neurodegeneration? 9
Back to the future: Epigenetic clock plasticity towards healthy aging 9
Emerging topics in C-elegans aging research: Transcriptional regulation, stress response and epigenetics 9
Resistin: A reappraisal 9
Emerging senolytic agents derived from natural products 9
Crucial players in Alzheimer's disease and diabetes mellitus: Friends or foes? 9
The impact of physical activity and sedentary behaviors on frailty levels 7
Frailty index as a biomarker of lifespan and healthspan: Focus on pharmacological interventions 7
Circulating miR-146a in healthy aging and type 2 diabetes: Age- and gender-specific trajectories 7
The ATF6 alpha arm of the Unfolded Protein Response mediates replicative senescence in human fibroblasts through a COX2/prostaglandin E-2 intracrine pathway 7
Centenarians as a model to discover genetic and epigenetic signatures of healthy ageing 7
Protein aggregates and proteostasis in aging: Amylin and beta-cell function 7
Age related depth profiles of human Stratum Corneum barrier-related molecular parameters by confocal Raman microscopy in vivo 7
Do sex differences in chronic disease underpin the sex-frailty paradox? 7
Transcriptome profiling of human papillary and reticular fibroblasts from adult interfollicular dermis pinpoints the 'tissue skeleton' gene network as a component of skin chrono-ageing 7
Ischemic stroke in neonatal and adult astrocytes 7
Extracellular vesicles as an emerging tool for the early detection of Alzheimer's disease 7
In situ evidence of cellular senescence in Thymic Epithelial Cells (TECs) during human thymic involution 7
Cortical control of upright stance in elderly 6
Iron status in the elderly: A review of recent evidence 6
Circadian clock as possible protective mechanism to pollution induced keratinocytes damage 6
Comparative analysis of the gut microbiota in centenarians and young adults shows a common signature across genotypically non-related populations 6
NF-kappa B signaling in skin aging 6
Effects of different hypoxia degrees on endothelial cell cultures-Time course study 6
Studying microRNAs in osteoarthritis: Critical overview of different analytical approaches 6
Geroprotectors: A role in the treatment of frailty 6
Modulation of cutaneous scavenger receptor B1 levels by exogenous stressors impairs in vitro wound closure 5