Methods

Methods

方法

  • 3区 中科院分区
  • Q1 JCR分区

高引用文章

文章名称 引用次数
Deep-Resp-Forest: A deep forest model to predict anti-cancer drug response 34
Deep learning in bioinformatics: Introduction, application, and perspective in the big data era 31
Bispecific T-cell engagers: Towards understanding variables influencing the in vitro potency and tumor selectivity and their modulation to enhance their efficacy and safety 21
Covalent labeling-mass spectrometry with non-specific reagents for studying protein structure and interactions 20
Gut metabolome meets microbiome: A methodological perspective to understand the relationship between host and microbe 18
Contemporary hydrogen deuterium exchange mass spectrometry 18
Engineering therapeutic bispecific antibodies using CrossMab technology 18
Functional microbiomics: Evaluation of gut microbiota-bile acid metabolism interactions in health and disease 17
Lensless digital holographic microscopy and its applications in biomedicine and environmental monitoring 16
Mass spectrometry-enabled structural biology of membrane proteins 16
Chemical methods for the modification of RNA 14
Separation of neural stem cells by whole cell membrane capacitance using dielectrophoresis 14
Microbial expression systems for membrane proteins 14
Predicting drug-disease associations and their therapeutic function based on the drug-disease association bipartite network 12
Determining mRNA half-lives on a transcriptome-wide scale 12
Purification of membrane proteins free from conventional detergents: SMA, new polymers, new opportunities and new insights 12
Affinity capillary electrophoresis for studying interactions in life sciences 11
Structural dynamics of protein S1 on the 70S ribosome visualized by ensemble cryo-EM 11
Current strategies for Site-Directed RNA Editing using ADARs 11
m-Health 2.0: New perspectives on mobile health, machine learning and big data analytics 10
Hidden motions and motion-induced invisibility: Dynamics-based spectral editing in solid-state NMR 10
3D structure determination of amyloid fibrils using solid-state NMR spectroscopy 10
Fluorescent indicator displacement assays to identify and characterize small molecule interactions with RNA 10
Second-generation fluorogenic RNA-based sensors 10
Cryo-electron microscopy of membrane proteins 10
FactorNet: A deep learning framework for predicting cell type specific transcription factor binding from nucleotide-resolution sequential data 10
Generation of conditional auxin-inducible degron (AID) cells and tight control of degron-fused proteins using the degradation inhibitor auxinole 10
RPAD (RNase R treatment, polyadenylation, and poly(A) plus RNA depletion) method to isolate highly pure circular RNA 10
Speech analysis for health: Current state-of-the-art and the increasing impact of deep learning 9
Implementing fast photochemical oxidation of proteins (FPOP) as a footprinting approach to solve diverse problems in structural biology 9
Unraveling co-translational protein folding: Concepts and methods 9
Methods of reconstitution to investigate membrane protein function 9
Sequencing-based methods for detection and quantitation of ribose methylations in RNA 8
RNA modifications in structure prediction - Status quo and future challenges 8
LC/MS at the whole protein level: Studies of biomolecular structure and interactions using native LC/MS and cross-path reactive chromatography (XP-RC) MS 8
Predicting Ion Mobility-Mass Spectrometry trends of polymers using the concept of apparent densities 8
In vitro reconstitution of translational arrest pathways 8
The imaging FCS diffusion law in the presence of multiple diffusive modes 8
The yin and yang of solubilization and stabilization for wild-type and full-length membrane protein 8
A reconstitution method for integral membrane proteins in hybrid lipid-polymer vesicles for enhanced functional durability 8
The genesis and evolution of bead-based multiplexing 7
Adventures with RNA graphs 7
Using bioreactors to study the effects of drugs on the human microbiota 7
Synthesis of multi-omit data and community metabolic models reveals insights into the role of hydrogen sulfide in colon cancer 7
How can native mass spectrometry contribute to characterization of biomacromolecular higher-order structure and interactions? 7
Molecular Dynamics simulations of the Strings and Binders Switch model of chromatin 7
Live-cell time-lapse imaging and single-cell tracking of in vitro cultured neural stem cells - Tools for analyzing dynamics of cell cycle, migration, and lineage selection 7
Thermophoresis for characterizing biomolecular interaction 7
A guide to nucleic acid detection by single-molecule kinetic fingerprinting 7
Systematic optimization of cell-free synthesized human endothelin B receptor folding 7