| Landscape of Tumor Mutation Load, Mismatch RepairDeficiency, and PD-L1 Expression in a Large Patient Cohort of Gastrointestinal Cancers |
41 |
| PARP1 Trapping by PARP Inhibitors Drives Cytotoxicity in Both Cancer Cells and Healthy Bone Marrow |
35 |
| Autocrine Fibronectin Inhibits Breast Cancer Metastasis |
34 |
| Exosomes from HNSCC Promote Angiogenesis through Reprogramming of Endothelial Cells |
32 |
| HPV Integration in HNSCC Correlates with Survival Outcomes, Immune Response Signatures, and Candidate Drivers |
29 |
| Ferroptosis-Induced Endoplasmic Reticulum Stress: Cross-talk between Ferroptosis and Apoptosis |
25 |
| PARP1 Trapping and DNA Replication Stress Enhance Radiosensitization with Combined WEE1 and PARP Inhibitors |
24 |
| Internalization of Exosomes through Receptor-Mediated Endocytosis |
24 |
| Effects of Oncogenic G alpha q and G alpha(11) Inhibition by FR900359 in Uveal Melanoma |
20 |
| Circular RNA ciRS-7 Maintains Metastatic Phenotypes as a ceRNA of miR-1299 to Target MMPs |
20 |
| Novel lncRNA LINC00844 Regulates Prostate Cancer Cell Migration and Invasion through AR Signaling |
19 |
| Methylation of the HOXA10 Promoter Directs miR-196b-5p-Dependent Cell Proliferation and Invasion of Gastric Cancer Cells |
19 |
| ABCC1-Exported Sphingosine-1-phosphate, Produced by Sphingosine Kinase Shortens Survival of Mice and Patients with Breast Cancer |
18 |
| miRNA-148a-3p Regulates Immunosuppression in DNA Mismatch Repair-Deficient Colorectal Cancer by Targeting PD-L1 |
18 |
| Small-Molecule Sigma1 Modulator Induces Autophagic Degradation of PD-L1 |
17 |
| A Role for Tryptophan-3-dioxygenase in CD8 T-cell Suppression and Evidence of Tryptophan Catabolism in Breast Cancer Patient Plasma |
17 |
| Ovarian Cancer Cells Commonly Exhibit Defective STING Signaling Which Affects Sensitivity to Viral Oncolysis |
16 |
| Periprostatic Adipose Tissue Favors Prostate Cancer Cell Invasion in an Obesity-Dependent Manner: Role of Oxidative Stress |
16 |
| CCR2 Chemokine Receptors Enhance Growth and Cell-Cycle Progression of Breast Cancer Cells through SRC and PKC Activation |
16 |
| c-MYC Drives Breast Cancer Metastasis to the Brain, but Promotes Synthetic Lethality with TRAIL |
15 |
| Precision Oncology beyond Targeted Therapy: Combining Omics Data with Machine Learning Matches the Majority of Cancer Cells to Effective Therapeutics |
15 |
| Biomarker Assessment of HR Deficiency, Tumor BRCA1/2 Mutations, and CCNE1 Copy Number in Ovarian Cancer: Associations with Clinical Outcome Following Platinum Monotherapy |
14 |
| Comparative Genomics Reveals Shared Mutational Landscape in Canine Hemangiosarcoma and Human Angiosarcoma |
14 |
| Dual Inhibition of CDK4 and CDK2 via Targeting p27 Tyrosine Phosphorylation Induces a Potent and Durable Response in Breast Cancer Cells |
13 |
| Targeting CDK1 and MEK/ERK Overcomes Apoptotic Resistance in BRAF-Mutant Human Colorectal Cancer |
13 |
| Mitotically-Associated lncRNA (MANCR) Affects Genomic Stability and Cell Division in Aggressive Breast Cancer |
13 |
| Human Organoids Share Structural and Genetic Features with Primary Pancreatic Adenocarcinoma Tumors |
13 |
| Association of USP10 with G3BP2 Inhibits p53 Signaling and Contributes to Poor Outcome in Prostate Cancer |
12 |
| Exosomes Induce Fibroblast Differentiation into Cancer-Associated Fibroblasts through TGF beta Signaling |
12 |
| De Novo Fatty Acid Synthesis-Driven Sphingolipid Metabolism Promotes Metastatic Potential of Colorectal Cancer |
12 |
| S1P Stimulates Proliferation byUpregulating CTGF Expression through S1PR2-Mediated YAP Activation |
12 |
| Molecular Portrait of Hypoxia in Breast Cancer: A Prognostic Signature and Novel HIF-Regulated Genes |
12 |
| Lipid Uptake Is an Androgen-Enhanced Lipid Supply Pathway Associated with Prostate Cancer Disease Progression and Bone Metastasis |
12 |
| Autophagy, Cell Viability, and Chemoresistance Are Regulated By miR-489 in Breast Cancer |
11 |
| Activation of AXL as a Preclinical Acquired Resistance Mechanism Against Osimertinib Treatment in EGFR-Mutant Non-Small Cell Lung Cancer Cells |
11 |
| Multi-omics Approach Reveals Distinct Differences in Left-and Right-Sided Colon Cancer |
11 |
| Heat Shock Protein 70 (Hsp70) Suppresses RIP1-Dependent Apoptotic and Necroptotic Cascades |
11 |
| Therapeutic Implications of p53 Status on Cancer Cell Fate Following Exposure to Ionizing Radiation and the DNA-PK Inhibitor M3814 |
11 |
| Genomic cfDNA Analysis of Aqueous Humor in Retinoblastoma Predicts Eye Salvage: The Surrogate Tumor Biopsy for Retinoblastoma |
11 |
| PI3K Positively Regulates YAP and TAZ in Mammary Tumorigenesis Through Multiple Signaling Pathways |
11 |
| Extracellular Fatty Acids Are the Major Contributor to Lipid Synthesis in Prostate Cancer |
11 |
| YB-1 Expression and Phosphorylation Regulate Tumorigenicity and Invasiveness in Melanoma by Influencing EMT |
11 |
| FBXO31 Suppresses Gastric Cancer EMT by Targeting Snail1 for Proteasomal Degradation |
11 |
| Epigenetically Regulated Chromosome 14q32 miRNA Cluster Induces Metastasis and Predicts Poor Prognosis in Lung Adenocarcinoma Patients |
10 |
| Centriole Overduplication is the Predominant Mechanism Leading to Centrosome Amplification in Melanoma |
10 |
| HIF-3 alpha Promotes Metastatic Phenotypes in Pancreatic Cancer by Transcriptional Regulation of the RhoC-ROCK1 Signaling Pathway |
10 |
| Elevated miR-182-5p Associates with Renal Cancer Cell Mitotic Arrest through Diminished MALAT-1 Expression |
10 |
| ALK Fusion Partners Impact Response to ALK Inhibition: Differential Effects on Sensitivity, Cellular Phenotypes, and Biochemical Properties |
10 |
| The Long (lncRNA) and Short (miRNA) of It: TGF beta-Mediated Control of RNA-Binding Proteins and Noncoding RNAs |
10 |
| Hyperactivation of MAPK Signaling Is Deleterious to RAS/RAF-mutant Melanoma |
10 |
