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HRA00129-C004, a Novel c-Met Antibody-Drug Conjugate, Exerts Encouraging Antitumor Activities and Favorable Safety Profile
Author: Tian, Yunan; Zhang, Jieqiong; Sun, Xing; Yang, Changyong; Liao, Cheng
Journal: MOLECULAR CANCER THERAPEUTICS. 2026; Vol. 25, Issue 3, pp. 371-385. DOI: 10.1158/1535-7163.MCT-24-0680
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Dual Inhibitors of KRASG12D and HSP90 Are Effective against KRASG12D Inhibitor Resistanc
Author: Pulido, Ines; Gunder, Laura C.; Ying, Chenghao; Wang, Yaya; Dai, Yan; Yang, Zimo; Rahnama, Alireza; Li, Jinhua; Sun, Yuetong; Liu, Chuhe; Zhou, Haoxin; Wang, Guoqiang; Foley, Kevin P.; Abdelhady, Khaled; Massad, Malek G.; Prince, Thomas L.; Papautsky, Ian; Ying, Weiwen; Shimamura, Takeshi
Journal: MOLECULAR CANCER THERAPEUTICS. 2026; Vol. 25, Issue 2, pp. 207-215. DOI: 10.1158/1535-7163.MCT-24-1173
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SDP-LIV1, a Novel and Optimized LIV-1 Antibody-Drug Conjugate Demonstrating Superior Antitumor Efficacy and a Favorable Safety Profile for the Treatment of Solid Tumor
Author: Peng, Yani; Yang, Changyong; Dong, Liwei; Sun, Xing; Zheng, Wei; Gong, Yanling; Shi, Qing; Ji, Ping; Chen, Simeng; Zhang, Wei; Liao, Cheng
Journal: MOLECULAR CANCER THERAPEUTICS. 2026; Vol. 25, Issue 2, pp. 322-332. DOI: 10.1158/1535-7163.MCT-24-0752
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Intratumoral Administration of Engineered circRNAs Encoding Cytosine Deaminase-Uracil Phosphoribosyltransferase and IL-15 Elicits Superior Antitumor Efficac
Author: Niu, Dun; Zhang, Shaotong; Ma, Xiaozhuang; Wu, Yaran; Zhu, Junshi; Ran, Jianglang; Shan, Meihua; Dai, Xufang; Lu, Lu; Yang, Mingzhen; Lian, Jiqin
Journal: MOLECULAR CANCER THERAPEUTICS. 2026; Vol. 25, Issue 2, pp. 272-282. DOI: 10.1158/1535-7163.MCT-25-0356
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A Novel Anti-CD47 Antibody TJH2201: Efficacious Tumor Suppression with Reduced RBC Toxicity via a SIRPα-Independent Mechanis
Author: Zhang, Huan; He, Fufan; Cao, Lei; Ni, Haiqing; Li, Ninghuan; Liu, Yang; Wu, Min; Liu, Ya; Wu, Bing; Li, Li; Wu, Zhihai; Ling, Xiaomin; Zhou, Shuaixiang; Li, Yiming; Deng, Shuxuan; Wu, Weiwei; Chu, Qian
Journal: MOLECULAR CANCER THERAPEUTICS. 2026; Vol. 25, Issue 1, pp. 21-33. DOI: 10.1158/1535-7163.MCT-25-0425
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Targeting the ERα DBD-LBD Interface with Mitoxantrone Disrupts Receptor Function through Proteasomal Degradatio
Author: Wang, Han; Luo, Yuxuan; Artham, Sandeep; Wang, Qianqian; Peng, Yi; Yun, Zixi; Li, Xinyue; Wu, Chen; Liu, Zhenghao; Weber-Bonk, Kristen L.; Pai, Chun-Peng; Cao, Yuan; Yue, Jiangan; Park, Sunghee; Keri, Ruth A.; Geng, Lisheng; Mcdonnell, Donald P.; Kao, Hung-Ying; Yang, Sichun
Journal: MOLECULAR CANCER THERAPEUTICS. 2026; Vol. 25, Issue 1, pp. 107-124. DOI: 10.1158/1535-7163.MCT-25-0405
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Targeting Monounsaturated Fatty Acid Metabolism for Radiosensitization of KRAS Mutant 3D Lung Cancer Model
Author: Lu, Shan; Pan, Xiao; Volckova, Eva; Shinde, Anjali; Fuller, Schuyler R.; Egan, Regina; Ma, Jianli; Kung, Jong; Ott, Christopher J.; Hata, Aaron N.; Benes, Cyril H.; Kang, Jing X.; Willers, Henning
Journal: MOLECULAR CANCER THERAPEUTICS. 2025; Vol. 24, Issue 6, pp. 920-930. DOI: 10.1158/1535-7163.MCT-24-0213
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NOC2L Promotes Paclitaxel Resistance in Various Types of Ovarian Cancers by Decreasing NDUFA4 through Histone Acetylation Suppressio
Author: Gu, Hao; Qi, Suwan; Chen, Jiaying; Wu, Hongqin; Xu, Jianjuan; Feng, Yaling
Journal: MOLECULAR CANCER THERAPEUTICS. 2025; Vol. 24, Issue 6, pp. 942-956. DOI: 10.1158/1535-7163.MCT-24-0512
