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Multivalent 28S rRNA expansion segments enable reconstitution of multilayered nucleolar architectur
Author: Wei, Jieli; Zhang, Yize; Wu, Jiaxin; Ye, Bingcheng; Fan, Xueyuan; Hu, Yucen; Hou, Zhonghuai; Xiang, ShengQi; Ma, Weirui
Journal: MOLECULAR CELL. 2026; Vol. 86, Issue 8, pp. 1459-1477. DOI: 10.1016/j.molcel.2026.03.023
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RNF25 confers mRNA damage tolerance by curbing activation of the integrated stress respons
Author: Zhao, Shubo; Palma-Chaundler, Chloe S.; Engel, Carla M.; Cordes, Jacqueline; Nixdorf, Daniel; Luo, Michael Y.; Kaya, Selay; Rahmanto, Aldwin Suryo; van den Heuvel, Diana; Mackens-Kiani, Timur; Weickert, Pedro; Lam, Simon; Gupta, Vipul; Philippou-Massier, Julia; Bagaric, Ivan; Bohlen, Jonathan; Hewitt, Graeme; Luijsterburg, Martijn S.; Beckmann, Roland; Beli, Petra; Nedialkova, Danny D.; Carnie, Christopher J.; Subklewe, Marion; Jackson, Stephen P.; Stingele, Julian
Journal: MOLECULAR CELL. 2026; Vol. 86, Issue 7, pp. 1275-1292. DOI: 10.1016/j.molcel.2026.02.024
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Filament-driven activation of the Kongming antiviral system by deoxyinosine triphosphat
Author: Zhen, Xiangkai; Li, Yu; Liu, Zihe; Huang, Yang; Xu, Shuying; Jiang, Yuchen; Li, Fan; Su, Jinfu; Lai, Qi; Li, Shaowei; Xia, Ningshao; Zheng, Qingbing; Ouyang, Songying
Journal: MOLECULAR CELL. 2026; Vol. 86, Issue 6, pp. 1134-1147. DOI: 10.1016/j.molcel.2026.01.026
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The XSER1 lncRNA acts as an enhancer RNA and confers resistance to pathogens by promoting chromatin loop formation in ric
Author: Yuan, Chao; Jiang, Jie; Cheng, Yu; Lian, Jian-Ping; Liao, Yu-Hong; Yu, Yang; Zhao, Wen-Long; Mo, Wan-Ting; Yang, Jia-Biao; Qin, Yi-Chao; Chen, Zheng-Tong; Yang, Lu; Lei, Meng-Qi; Zhang, Yu-Chan; He, Rui-Rui; Zhou, Yan-Fei; Chen, Yue-Qin
Journal: MOLECULAR CELL. 2026; Vol. 86, Issue 6, pp. 998-1014. DOI: 10.1016/j.molcel.2026.02.013
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Filament-mediated repurposing of toxic dITP for immunity in the Kongming syste
Author: Feng, Hao; Shao, Kai; Zeng, Zhifeng; Tan, Eddie Yong Jun; Hu, Zeyu; Zhao, Ruiliang; Rao, Jikai; Shi, Jian; Chen, Zhuojian; Redondo, Rafael Pinilla; Wu, Bin; Han, Wenyuan; Luo, Min
Journal: MOLECULAR CELL. 2026; Vol. 86, Issue 6, pp. 1148-1163. DOI: 10.1016/j.molcel.2026.01.027
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ER-tethering directs TREX1 penetration of a barrier at micronucle
Author: Chen, Yanyang; Norman, Roshan Xavier; Toufektchan, Eleonore; Luan, Xiaohan; Shim, Abraham; Rosenberg, Hannah; Kovacs, Marton Tibor; Nichols, Ashley; Hickling, James; Cifani, Paolo; Kentsis, Alex; Zhou, Wen; Maciejowski, John
Journal: MOLECULAR CELL. 2026; Vol. 86, Issue 6, pp. 1099-1115. DOI: 10.1016/j.molcel.2026.02.012
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Global mapping of circRNA-target RNA interactions reveal P-body-mediated translational repressio
Author: Li, Peng; Zhang, Hongmei; Cai, Zhaokui; Zhang, Yuyang; Yang, Ruiyun; Ye, Rong; Li, Jingxin; Zhao, Hailian; Liu, Bowen; Yuan, Zhen; Li, Xuekun; Wang, Xi; Zhu, Ping; Xue, Yuanchao
Journal: MOLECULAR CELL. 2026; Vol. 86, Issue 5, pp. -. DOI: 10.1016/j.molcel.2026.01.018
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Structural basis for Cas9-directed spacer acquisition in type II-A CRISPR-Cas system
Author: Li, Zhaoxing; Li, Yutao; Kong, Jianping; Wu, Qianqian; Huang, Pingping; Zhang, Yu; Wu, Wanqian; Chen, Meirong; Liu, Yongfeng; Lin, Hanfeng; Hou, Liqiu; Liu, Gongyu; Zeng, Ting; He, Yutong; Hu, Chunyi; Yang, Zhenhuang; Lu, Meiling; Luo, Min; Xiao, Yibei
Journal: MOLECULAR CELL. 2026; Vol. 86, Issue 5, pp. -. DOI: 10.1016/j.molcel.2026.01.024
