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A subunit-selective negative allosteric modulator of GluN1/GluN3A glycine-activated recepto
Author: Jacobs, Leon; Nguyen, Trangkimberly T.; Mccallum, Adam; Epplin, Matt P.; Perszyk, Riley E.; Myers, Scott J.; Liu, Ken; Yang, Yanli; Van Der Westhuyzen, Aletta E.; Nocilla, Kelsey A.; Allen, James; Ullman, Elijah Z.; Liu, Ding; Du, Yufei; Yuan, Hongjie; Liotta, Dennis C.; Traynelis, Stephen F
Journal: MOLECULAR PHARMACOLOGY. 2026; Vol. 108, Issue 3, pp. -. DOI: 10.1016/j.molpha.2026.100104
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Cepharanthine, a valuable sanative alternative for hepatocellular carcinoma through regulating Hippo-Yes-associated protein signal transductio
Author: Hu, Kejun; Zhao, Yukai; Fu, Xinyu; Li, Sai; Wu, Ting; Liu, Wangwang; Wang, Wei; Cheng, Cheng; Qiu, Huanhuan; Pan, Shumin; Lv, Qi; Xu, Guanglin
Journal: MOLECULAR PHARMACOLOGY. 2026; Vol. 108, Issue 3, pp. -. DOI: 10.1016/j.molpha.2026.100105
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Fenofibrate promotes erucic acid metabolism by peroxisome enzyme EHHADH activation alleviating high-fat diet-induced steatotic liver diseas
Author: Jin, Ming; Zhang, Rongmi; Xin, Wenwen; Sun, Li; Fan, Xue; Lu, Qian; Zhang, Luyong; Jiang, Zhenzhou; Yu, Qinwei
Journal: MOLECULAR PHARMACOLOGY. 2025; Vol. 107, Issue 7, pp. -. DOI: 10.1016/j.molpha.2025.100047
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Cyclovirobuxine inhibits ferroptosis to mitigate Alzheimer disease in glutamate-induced SH-SY5Y cell: the role of the liquid-liquid phase separation of FTH
Author: Wang, Fuwei; Zhou, Qiong; Chen, Zihao; Xie, Lihua; Zheng, Nan; Chen, Ziwen; Sun, Qiang; Du, Jikun; Lin, Jiantao; Li, Baohong; Li, Li
Journal: MOLECULAR PHARMACOLOGY. 2025; Vol. 107, Issue 7, pp. -. DOI: 10.1016/j.molpha.2025.100046
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Upregulating vascular endothelial KCa2.3 channels alleviates pulmonary hypertension in mic
Author: Han, Meng-Zhuan; Wang, Yan; Sun, Ke-Xin; Zhang, Yong-Jian; Bai, Ru-Yue; Wu, Lin-Hong; Hai, Xia-Xia; Lai, Bao-Chang; Li, Jing-Jing; She, Gang; Zhang, Yi; Du, Xiao-Jun; Pang, Zheng-Da; Deng, Xiu-Ling
Journal: MOLECULAR PHARMACOLOGY. 2025; Vol. 107, Issue 7, pp. -. DOI: 10.1016/j.molpha.2025.100048
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Extracellular ATP increases agonist potency and reduces latency at class B G protein-coupled receptor
Author: Zhu, Shuying; Yuan, Alice; Duffy, Tristan; Kim, Brandon H.; Ozawa, Takeaki; Dixon, S. Jeffrey; Chidiac, Peter
Journal: MOLECULAR PHARMACOLOGY. 2025; Vol. 107, Issue 6, pp. -. DOI: 10.1016/j.molpha.2025.100040
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Doxorubicin-induced apoptosis is exacerbated by MG53 and associated with altered Akt signaling in H9c2 cell
Author: Xu, Bowen; Li, Hongye; Chen, Hongping; Ren, Yanxin; Li, Jun; Gong, Lei; Zhong, Lin; Yang, Jun
Journal: MOLECULAR PHARMACOLOGY. 2025; Vol. 107, Issue 5, pp. -. DOI: 10.1016/j.molpha.2025.100032
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Evaluation of allosteric N-methyl-D-aspartate receptor modulation by GluN2A-selective antagonists using pharmacological equilibrium modelin
Author: Lotti, James S.; Jones, Jaron; Farnsworth, Jill C.; Yi, Feng; Zhao, Fabao; Menniti, Frank S.; Volkmann, Robert A.; Clausen, Rasmus P.; Hansen, Kasper B.
Journal: MOLECULAR PHARMACOLOGY. 2025; Vol. 107, Issue 1, pp. -. DOI: 10.1124/molpharm.124.000975
