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Native cell niche-inspired multiordernanoassemblies orchestrate integrated interaction networks to guide muscle regeneratio
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Journal: MOLECULAR THERAPY. 2026; Vol. 34, Issue 4, pp. 2081-2097. DOI: 10.1016/j.ymthe.2025.12.044
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Mitochondrial citrate transport represents a metabolic liability in MYCN-amplified neuroblastom
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A synthetic hyperglycemia-sensing gene circuit enhances blood glucose homeostasis in diabetic mic
Author: Zhang, Yuan; Deng, Shuai; Zhu, Yanlun; Li, Xu; Deng, Jiani; Wang, Chengdong; Sun, Jianmin; Bao, Feixiang; Tang, Shibing; Ye, Haifeng; Chan, Hon Fai; Zhao, Hui
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Basic enables selection-free efficient knockin of DNA in human T cell
Author: Wang, Kexin; Li, Xiaorui; Li, Jin; Yu, Zhuoying; Li, Pan; Xie, Yuyang; Liu, Jinxin; Huang, Honglin; Zhang, Shanshan; Ma, Wenju; Gao, Fei; Du, Xuguang; Wang, Jianxun; Capecchi, Mario R.; Wu, Sen
Journal: MOLECULAR THERAPY. 2026; Vol. 34, Issue 4, pp. 2309-2323. DOI: 10.1016/j.ymthe.2025.12.064
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Intravenous administration of EXG110 resulted in substrate correction in Fabry mice and sustained enzyme activity in non-human primate
Author: Li, Shaoyong; Yu, Pengfei; Wang, Hong; Liu, Mingwen; Wang, Qingzeng; Li, Zhongwan; Chen, Shuyuan; He, Chentao; Zhan, Bryan Yue; Tong, Lucas Song; Shou, Xinyi; Luo, Jingjing; Jia, Xiaoyuan; Xin, Xin; Hu, Wei; Lu, Zhihong; Wang, Yigang; Ye, Guojie; Mao, Jianhua; Wu, Zhenhua
Journal: MOLECULAR THERAPY. 2026; Vol. 34, Issue 4, pp. 1997-2011. DOI:
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A CD40-OX40 co-stimulatory circuit orchestrates protective CD4+T cell immunity in tuberculosi
Author: Zhang, Ximeng; Yang, Jing; Li, Fuxiang; Wang, Yu; Li, Zhaodong; Wang, Wenfei; Hu, Yunlong; Shi, Chenyan; Pan, Fan; Feng, Carl G; Wang, Yejun; Yang, Qianting; Chen, Xinchun; Cai, Yi
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Allergen-specific immunotherapy with Der p 1/2 mRNA vaccines relieves house-dust-mite-induced allergic airway inflammation in a mouse mode
Author: Li, Junda; Ru, Yi; Yi, Xilian; Guan, Kai; Li, Xiaogang; Yin, Jia
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CD96 as a therapeutic target for CAR T cell therapy in acute myeloid leukemi
Author: Gao, Xiaotong; Liu, Hailing; Li, Guokun; Zhou, Yali; Dong, Yan; Chen, Xiao; Fan, Wen; Li, Erbing; Wang, Sanmei; Luan, Qinyao; Zhang, Jing; Jin, Hui; Liao, Hui; Luo, Yizhou; Liu, Li; Qin, Weiwei; Ren, Jiangtao; Li, Jianyong; Fan, Lei
Journal: MOLECULAR THERAPY. 2026; Vol. 34, Issue 4, pp. 2201-2216. DOI: 10.1016/j.ymthe.2025.12.058
