| Dominant-Negative TGF-beta Receptor Enhances PSMA-Targeted Human CAR T Cell Proliferation And Augments Prostate Cancer Eradication |
70 |
| Delivering the Messenger: Advances in Technologies for Therapeutic mRNA Delivery |
68 |
| Systemic AAV Micro-dystrophin Gene Therapy for Duchenne Muscular Dystrophy |
58 |
| circRNA_0025202 Regulates Tamoxifen Sensitivity and Tumor Progression via Regulating the miR-182-5p/FOXO3a Axis in Breast Cancer |
53 |
| Mesenchymal Stem Cell-Based Therapy for Cardiovascular Disease: Progress and Challenges |
41 |
| Self-Amplifying RNA Vaccines Give Equivalent Protection against Influenza to mRNA Vaccines but at Much Lower Doses |
41 |
| A Novel Amino Lipid Series for mRNA Delivery: Improved Endosomal Escape and Sustained Pharmacology and Safety in Non-human Primates |
40 |
| In Vivo Fate and Activity of Second- versus Third-Generation CD19-Specific CAR-T Cells in B Cell Non-Hodgkin's Lymphomas |
40 |
| mRNA as a Transformative Technology for Vaccine Development to Control Infectious Diseases |
34 |
| Analyzing the Interactions of mRNAs and ncRNAs to Predict Competing Endogenous RNA Networks in Osteosarcoma Chemo-Resistance |
33 |
| Exosome-Derived miR-130a Activates Angiogenesis in Gastric Cancer by Targeting C-MYB in Vascular Endothelial Cells |
33 |
| Advanced siRNA Designs Further Improve In Vivo Performance of GaINAc-siRNA Conjugates |
33 |
| Exosomes Produced from 3D Cultures of MSCs by Tangential Flow Filtration Show Higher Yield and Improved Activity |
32 |
| Combination Immunotherapy of MUC1 mRNA Nano-vaccine and CTLA-4 Blockade Effectively Inhibits Growth of Triple Negative Breast Cancer |
31 |
| Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity |
30 |
| The GPI-Linked Protein LY6A Drives AAV-PHP.B Transport across the Blood-Brain Barrier |
30 |
| DANCR Promotes Metastasis and Proliferation in Bladder Cancer Cells by Enhancing IL-11-STAT3 Signaling and CCND1 Expression |
29 |
| Phase I Study of Lentiviral-Transduced Chimeric Antigen Receptor-Modified T Cells Recognizing Mesothelin in Advanced Solid Cancers |
27 |
| Optimization of IL13R alpha 2-Targeted Chimeric Antigen Receptor T Cells for Improved Anti-tumor Efficacy against Glioblastoma |
27 |
| A Positive Feed-Forward Loop between LncRNA-CYTOR and Wnt/beta-Catenin Signaling Promotes Metastasis of Colon Cancer |
27 |
| TGF-beta Mediates Renal Fibrosis via the Smad3-Erbb4-IR Long Noncoding RNA Axis |
26 |
| Low-Dose Radiation Conditioning Enables CAR T Cells to Mitigate Antigen Escape |
26 |
| Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes by Soluble Factors from Human Mesenchymal Stem Cells |
26 |
| Immunological Synapse Predicts Effectiveness of Chimeric Antigen Receptor Cells |
26 |
| Hypoxic Glioma Cell-Secreted Exosomal miR-301a Activates Wnt/beta-catenin Signaling and Promotes Radiation Resistance by Targeting TCEAL7 |
26 |
| Superagonist IL-15-Armed Oncolytic Virus Elicits Potent Antitumor Immunity and Therapy That Are Enhanced with PD-1 Blockade |
26 |
| Chimeric Antigen Receptor-Engineered Human Gamma Delta T Cells: Enhanced Cytotoxicity with Retention of Cross Presentation |
25 |
| Exosomes Serve as Nanoparticles to Deliver Anti-miR-214 to Reverse Chemoresistance to Cisplatin in Gastric Cancer |
25 |
| ncRNA-Encoded Peptides or Proteins and Cancer |
24 |
| Hypoxic Lung-Cancer-Derived Extracellular Vesicle MicroRNA-103a Increases the Oncogenic Effects of Macrophages by Targeting PTEN |
24 |
| Retinal AAV8-RS1 Gene Therapy for X-Linked Retinoschisis: Initial Findings from a Phase I/IIa Trial by Intravitreal Delivery |
24 |
| Circular RNAs: A Novel Class of Functional RNA Molecules with a Therapeutic Perspective |
24 |
| circRNA.33186 Contributes to the Pathogenesis of Osteoarthritis by Sponging miR-127-5p |
23 |
| Exosome-Mediated Small RNA Delivery: A Novel Therapeutic Approach for Inflammatory Lung Responses |
23 |
| Triple Vectors Expand AAV Transfer Capacity in the Retina |
23 |
| Risk-Associated Long Noncoding RNA FOXD3-AS1 Inhibits Neuroblastoma Progression by Repressing PARP1-Mediated Activation of CTCF |
22 |
| Dose-Dependent Prevention of Metabolic and Neurologic Disease in Murine MPS II by ZFN-Mediated In Vivo Genome Editing |
22 |
| AAV5-miHTT Gene Therapy Demonstrates Broad Distribution and Strong Human Mutant Huntingtin Lowering in a Huntington's Disease Minipig Model |
22 |
| Oncolytic Virus Combination Therapy: Killing One Bird with Two Stones |
22 |
| Exosomes from Endothelial Progenitor Cells Improve the Outcome of a Murine Model of Sepsis |
22 |
| Pre-existing Immunity to Oncolytic Virus Potentiates Its Immunotherapeutic Efficacy |
21 |
| Stem Cell Secretome and Its Effect on Cellular Mechanisms Relevant to Wound Healing |
21 |
| Correction of the Marfan Syndrome Pathogenic FBN1 Mutation by Base Editing in Human Cells and Heterozygous Embryos |
21 |
| Delivery of Anti-miRNA for Triple-Negative Breast Cancer Therapy Using RNA Nanoparticles Targeting Stem Cell Marker CD133 |
21 |
| In Situ Gene Therapy via AAV-CRISPR-Cas9-Mediated Targeted Gene Regulation |
21 |
| Lipid Nanoparticle-Delivered Chemically Modified mRNA Restores Chloride Secretion in Cystic Fibrosis |
21 |
| Promoter Methylation-Regulated miR-145-5p Inhibits Laryngeal Squamous Cell Carcinoma Progression by Targeting FSCN1 |
20 |
| Development and Evaluation of an Optimal Human Single-Chain Variable Fragment-Derived BCMA-Targeted CAR T Cell Vector |
20 |
| Exosome-Mediated miR-29 Transfer Reduces Muscle Atrophy and Kidney Fibrosis in Mice |
20 |
| A Novel Anti-LILRB4 CAR-T Cell for the Treatment of Monocytic AML |
19 |
