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A unique CD4+ T cell subset expressing granzyme K is regulated by transcription factor EOMES and important for T cell-mediated intestinal inflammatio
Author: Xie, Tian; Du, Yizhou; Wang, Qihan; Zhang, Hao; Wei, Kun; Chi, Xinxin; Bai, Xue; Fu, Yujie; Peng, Zhilin; Zhu, Yicheng; Lan, Qiuyan; Dong, Chen
Journal: NATURE IMMUNOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1038/s41590-026-02479-6
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Purine salvage pathway protects CD8+ T cells from metabolic stres
Author: Tajima, Masaki; Hao, He; Zhang, Baihao; Matsuoka, Yuta; Sonomura, Kazuhiro; Imami, Koshi; Isobe, Yosuke; Maeda, Rae; Lin, Yu-Hsien; Shimba, Akihiro; Kato, Ryoma; Costa Cruz, Pedro Henrique; Washizu, Sayaka; Ikejiri, Yosuke; Morinibu, Akiyo; Barker, Clive Steven; Seita, Jun; Wu, Yibo; Ito, Satomi; Narushima, Seiko; Nakano, Rei; Maruya, Mikako; Kobayashi, Wakana; Narayanan, Sai Shanmukha Priya; Shaheen, Jumana; Neyama, Hiroyuki; Yamada, Ken-ichi; Arita, Makoto; Sugiura, Yuki; Fagarasan, Sidonia
Journal: NATURE IMMUNOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1038/s41590-026-02491-w
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Tumor-derived branched-chain α-keto acids activate Notch signaling in tumor-associated macrophages to limit immunit
Author: Ma, Qi-Xiang; Zhao, Ru; Han, Jiang-Xue; Zhu, Wen-Ying; Xu, Mi-Die; Zhang, Xiao-Yan; Yan, Guo-Quan; Wen, Wen-Yu; Han, Guang-Chun; Luo, Min; Yin, Miao; Li, Jin-Tao; Lei, Qun-Ying
Journal: NATURE IMMUNOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1038/s41590-026-02484-9
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BLIMP1 shapes germinal center B cell clonal diversity by gating chromatin accessibility during light-to-dark zone transitio
Author: Manakkat Vijay, Godhev Kumar; Ramaswami, Bala; Gierlack, Steven; Pease, Nicholas A.; Gerges, Peter; Chen, Dianyu; Thakkar, Kairavee; Mena Hernandez, Luis; Keshari, Swapnil; Xu, Heping; Salomonis, Nathan; Das, Jishnu; Rothstein, David M.; Singh, Harinder
Journal: NATURE IMMUNOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1038/s41590-026-02495-6
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Immunopeptidome profiling in pulmonary fibrosis provides a platform for identifying therapeutic target
Author: Bai, Ziyi; Lan, Tianxia; Hong, Weiqi; Que, Haiying; Zhu, Min; Xiao, Xin; Wan, Dandan; Ai, Jiayuan; Huang, Shaoxiong; Wang, Jiayu; Hong, Qiaonan; Liu, Yanyan; Xiao, Chengxin; Zhao, Chengjian; Wang, Xin; Zhang, Xiaolong; Yang, Ting; Xu, Heng; Dai, Lunzhi; Powell, Charles A.; Richeldi, Luca; Luo, Fengming; Dong, Haohao; Yuan, Yong; Pu, Qiang; Wei, Xiawei
Journal: NATURE IMMUNOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1038/s41590-026-02501-x
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IL-9 and Blimp-1 protect the transcriptional identity of group 2 innate lymphocytes in allergic asthm
Author: Zheng, Yibo; Giri, Shilpi; Zhang, Jinyi; Chen, Yijia; Yang, Aaron; Kale, Sagar L.; Beeravolu, Harshita; Pannucci, Abbe; Marinov, Anthony D.; Tilstra, Jeremy S.; He, Kun; Creech, Arianna; Schwartz, Daniella M.; Gottschalk, Rachel A.; Bouladoux, Nicolas; Belkaid, Yasmine; Cillo, Anthony R.; Ray, Anuradha; Poholek, Amanda C
Journal: NATURE IMMUNOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1038/s41590-026-02509-3
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Lymphocyte-derived cholinergic circuits modulate germinal center output and B cell activatio
Author: Nechanitzky, Duygu; Smith, Logan K.; Nechanitzky, Robert; Jafari, Soode Moghadas; Haight, Jillian; Bontoux, Christophe; Ramachandran, Parameswaran; Gold, Matthew J.; Wakeham, Andrew C.; Saunders, Mary E.; Deniset, Justin F.; Mak, Tak W
Journal: NATURE IMMUNOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1038/s41590-026-02444-3
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Sparcl1 mitigates abdominal aortic aneurysm through inhibiting lymphangiogenesis-mediated TLS formatio
Author: Chen, Mei-Hua; Hua, Yi-Jie; Li, Yan; Lei, Yu; Zhou, Si-Yuan; Hu, Xi-De; Hu, Dong-Hua; Dong, Zhi-Hui; Lu, Yan; Zhuang, Tao; Ruan, Cheng-Chao
Journal: NATURE IMMUNOLOGY. 2026; Vol. , Issue , pp. -. DOI: 10.1038/s41590-026-02454-1
