| Myeloid-derived suppressor cells coming of age |
205 |
| Subsets of exhausted CD8(+) T cells differentially mediate tumor control and respond to checkpoint blockade |
139 |
| Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity |
135 |
| Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage |
122 |
| The immunology of hepatocellular carcinoma |
114 |
| The twilight of immunity: emerging concepts in aging of the immune system |
113 |
| Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry |
93 |
| Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction |
87 |
| Regulatory T cells in autoimmune disease |
83 |
| The immune cell landscape in kidneys of patients with lupus nephritis |
72 |
| Metabolic reprogramming of natural killer cells in obesity limits antitumor responses |
71 |
| Single-cell RNA-seq reveals TOX as a key regulator of CD8(+) T cell persistence in chronic infection |
64 |
| The Ca2+ sensor STIM1 regulates the type I interferon response by retaining the signaling adaptor STING at the endoplasmic reticulum |
56 |
| Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression |
56 |
| Recent progress in broadly neutralizing antibodies to HIV |
56 |
| Engagement of MHC class I by the inhibitory receptor LILRB1 suppresses macrophages and is a target of cancer immunotherapy |
55 |
| Innate immunity to intracellular LPS |
54 |
| Tissue signals imprint ILC2 identity with anticipatory function |
54 |
| The biology and functional importance of MAIT cells |
54 |
| Innate immune responses to trauma |
53 |
| Targeting immune cell circuits and trafficking in inflammatory bowel disease |
52 |
| NKILA lncRNA promotes tumor immune evasion by sensitizing T cells to activation-induced cell death |
52 |
| Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways |
50 |
| Reassessing B cell contributions in multiple sclerosis |
49 |
| Single-cell gene expression reveals a landscape of regulatory T cell phenotypes shaped by the TCR |
48 |
| Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells |
47 |
| Tumor immunoevasion via acidosis-dependent induction of regulatory tumor-associated macrophages |
45 |
| The gamma delta TCR combines innate immunity with adaptive immunity by utilizing spatially distinct regions for agonist selection and antigen responsiveness |
45 |
| PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1(+)CD38(hi) cells and anti-PD-1 resistance |
44 |
| Regulation of macrophage immunometabolism in atherosclerosis |
43 |
| Mechanisms of immunotherapy resistance: lessons from glioblastoma |
43 |
| m(6)A modification controls the innate immune response to infection by targeting type I interferons |
43 |
| Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47-mediated 'don't-eat-me' signal |
42 |
| The epithelial immune microenvironment (EIME) in atopic dermatitis and psoriasis |
41 |
| The identity and function of microglia in neurodegeneration |
40 |
| gamma delta T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis |
40 |
| Adaptive plasticity of IL-10(+) and IL-35(+) T-reg cells cooperatively promotes tumor T cell exhaustion |
39 |
| Natural killer cell specificity for viral infections |
39 |
| Inhibitory receptors and ligands beyond PD- PD-L1 and CTLA-4: breakthroughs or backups |
39 |
| Macrophage de novo NAD(+) synthesis specifies immune function in aging and inflammation |
39 |
| Distinct progenitor lineages contribute to the heterogeneity of plasmacytoid dendritic cells |
38 |
| Regulatory T cells mediate specific suppression by depleting peptide-MHC class II from dendritic cells |
38 |
| Environmental allergens induce allergic inflammation through proteolytic maturation of IL-33 |
38 |
| Human CD8(+) T cell cross-reactivity across influenza A, B and C viruses |
38 |
| Epigenetic control of innate and adaptive immune memory |
37 |
| Local proliferation maintains a stable pool of tissue-resident memory T cells after antiviral recall responses |
37 |
| The influence of the microbiome on respiratory health |
37 |
| Intravital mucosal imaging of CD8(+) resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory |
35 |
| Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses |
35 |
| Tissue-resident memory T cells at the center of immunity to solid tumors |
35 |
| Listeria hijacks host mitophagy through a novel mitophagy receptor to evade killing |
35 |
| Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors |
35 |
| The immune response against flaviviruses |
34 |
| Re-evaluating microglia expression profiles using RiboTag and cell isolation strategies |
33 |
| The establishment of resident memory B cells in the lung requires local antigen encounter |
33 |
| G3BP1 promotes DNA binding and activation of cGAS |
32 |
| Hematopoietic progenitor cells as integrative hubs for adaptation to and fine-tuning of inflammation |
32 |
| DEL-1 promotes macrophage efferocytosis and clearance of inflammation |
32 |
| Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing T-reg cells through modification of the intestinal microbiota |
32 |
| Endogenous glucocorticoids control host resistance to viral infection through the tissue-specific regulation of PD-1 expression on NK cells |
32 |
| c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies |
32 |
| Functional reprogramming of regulatory T cells in the absence of Foxp3 |
32 |
| Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation |
31 |
| gamma delta TCR ligands: the quest to solve a 500-million-year-old mystery |
30 |
| The long noncoding RNA Lnczc3h7a promotes a TRIM25-mediated RIG-I antiviral innate immune response |
30 |
| RIP kinases as modulators of inflammation and immunity |
30 |
| Subsets of ILC3-ILC1-like cells generate a diversity spectrum of innate lymphoid cells in human mucosal tissues |
30 |
| Inflammatory macrophage dependence on NAD(+) salvage is a consequence of reactive oxygen species-mediated DNA damage |
30 |
| Interferon target-gene expression and epigenomic signatures in health and disease |
29 |
| Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity |
29 |
| The immunoproteasome and thymoproteasome: functions, evolution and human disease |
29 |
| Follicular regulatory T cells control humoral and allergic immunity by restraining early B cell responses |
29 |
| Thymic regulatory T cells arise via two distinct developmental programs |
29 |
| Inflammation induced by influenza virus impairs human innate immune control of pneumococcus |
28 |
| Plasmacytoid dendritic cells develop from Ly6D(+) lymphoid progenitors distinct from the myeloid lineage |
28 |
| Single-cell analysis reveals the continuum of human lympho-myeloid progenitor cells |
28 |
| Tumor-derived exosomes antagonize innate antiviral immunity |
28 |
| Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway |
28 |
| Memory CD4(+) T cells are generated in the human fetal intestine |
28 |
| Inhibition of the dipeptidyl peptidase DPP4 (CD26) reveals IL-33-dependent eosinophil-mediated control of tumor growth |
28 |
| Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency |
27 |
| Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza |
27 |
| CARD9(+) microglia promote antifungal immunity via IL-1 beta- and CXCL1-mediated neutrophil recruitment |
27 |
| IL-13 secreted by ILC2s promotes the self-renewal of intestinal stem cells through circular RNA circPan3 |
27 |
| LAG-3 inhibits the activation of CD4(+) T cells that recognize stable pMHCII through its conformation-dependent recognition of pMHCII |
26 |
| c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4(+) T cells |
26 |
| PTPN2 regulates the generation of exhausted CD8(+) T cell subpopulations and restrains tumor immunity |
25 |
| Unique pattern of neutrophil migration and function during tumor progression |
25 |
| The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation |
24 |
| Antibody-mediated protection against Ebola virus |
24 |
| Hobit- and Blimp-1-driven CD4(+) tissue-resident memory T cells control chronic intestinal inflammation |
24 |
| c-Maf-dependent T-reg cell control of intestinal T(H)17 cells and IgA establishes host-microbiota homeostasis |
23 |
| Malaria prevention: from immunological concepts to effective vaccines and protective antibodies |
23 |
| Mitochondrial fragmentation limits NK cell-based tumor immunosurveillance |
23 |
| The effect of cellular context on miR-155-mediated gene regulation in four major immune cell types |
23 |
| Adaptation and memory in immune responses |
22 |
| A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape |
22 |
| SUCNR1 controls an anti-inflammatory program in macrophages to regulate the metabolic response to obesity |
22 |
| Recognition of microbial viability via TLR8 drives T-FH cell differentiation and vaccine responses |
22 |
| IL-17 receptor-based signaling and implications for disease |
22 |
| Cross-specificity of protective human antibodies against Klebsiella pneumoniae LPS O-antigen |
22 |
| Regulatory T cell adaptation in the intestine and skin |
21 |
| Dynamic changes to lipid mediators support transitions among macrophage subtypes during muscle regeneration |
21 |
| Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children |
21 |
| B cell signaling in context |
21 |
| Humanized immune system mouse models: progress, challenges and opportunities |
21 |
| Vaccine hesitancy and coercion: all eyes on France |
21 |
| CCR5AS lncRNA variation differentially regulates CCR influencing HIV disease outcome |
21 |
| Metabolic adaptations of tissue-resident immune cells |
21 |
| The transcription factor c-Maf is essential for the commitment of IL-17-producing gamma delta T cells |
21 |
| Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses |
20 |
| Cryptic activation of an Irf8 enhancer governs cDC1 fate specification |
20 |
| Interferon-lambda modulates dendritic cells to facilitate T cell immunity during infection with influenza A virus |
20 |
| Epigenetic programming underpins B cell dysfunction in human SLE |
20 |
| Macrophages, rather than DCs, are responsible for inflammasome activity in the GM-CSF BMDC model |
20 |
| N-myristoyltransferase deficiency impairs activation of kinase AMPK and promotes synovial tissue inflammation |
20 |
| Second signals rescue B cells from activation-induced mitochondrial dysfunction and death |
20 |
| Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans |
20 |
| Human germinal center transcriptional programs are de-synchronized in B cell lymphoma |
19 |
| RNA-binding proteins control gene expression and cell fate in the immune system |
19 |
| The transcription factor c-Myb regulates CD8(+) T cell stemness and antitumor immunity |
19 |
| Emerging viral diseases from a vaccinology perspective: preparing for the next pandemic |
19 |
| Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-beta signaling |
19 |
| House dust mites activate nociceptor-mast cell clusters to drive type 2 skin inflammation |
19 |
| Quantitative analysis of T cell proteomes and environmental sensors during T cell differentiation |
18 |
| The IRE1 endoplasmic reticulum stress sensor activates natural killer cell immunity in part by regulating c-Myc |
18 |
| Mouse cytomegalovirus-experienced ILC1s acquire a memory response dependent on the viral glycoprotein m12 |
18 |
| Connecting blood and intratumoral T-reg cell activity in predicting future relapse in breast cancer |
18 |
| Selective autophagy of the adaptor TRIF regulates innate inflammatory signaling |
18 |
| Chemokines and integrins independently tune actin flow and substrate friction during intranodal migration of T cells |
18 |
| Deciphering CD4(+) T cell specificity using novel MHC-TCR chimeric receptors |
17 |
| Thymic tolerance as a key brake on autoimmunity |
17 |
| Epithelial damage and tissue gamma delta T cells promote a unique tumor-protective IgE response |
17 |
| Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration |
17 |
| An immunoregulatory and tissue-residency program modulated by c-MAF in human T(H)17 cells |
17 |
| Glycerol phosphate shuttle enzyme GPD2 regulates macrophage inflammatory responses |
17 |
| Human retinoic acid-regulated CD161(+) regulatory T cells support wound repair in intestinal mucosa |
17 |
| Myeloid-derived suppressor cells control B cell accumulation in the central nervous system during autoimmunity |
17 |
| Alarmin S100A11 initiates a chemokine response to the human pathogen Toxoplasma gondii |
17 |
| Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics |
16 |
| Diversification of human plasmacytoid predendritic cells in response to a single stimulus |
16 |
| Lymph node conduits transport virions for rapid T cell activation |
16 |
| Interferon-lambda enhances adaptive mucosal immunity by boosting release of thymic stromal lymphopoietin |
16 |
| The value of transcriptomics in advancing knowledge of the immune response and diagnosis in tuberculosis |
16 |
| An Nfil3-Zeb2-Id2 pathway imposes Irf8 enhancer switching during cDC1 development |
16 |
| Inducible degradation of lncRNA Sros1 promotes IFN-gamma-mediated activation of innate immune responses by stabilizing Stat1 mRNA |
16 |
| An essential role for the Zn2+ transporter ZIP7 in B cell development |
15 |
| Atad3a suppresses Pink1-dependent mitophagy to maintain homeostasis of hematopoietic progenitor cells |
15 |
| A tumor-myeloid cell axis, mediated via the cytokines IL-1 alpha and TSLP, promotes the progression of breast cancer |
15 |
| The transcription factor TCF-1 enforces commitment to the innate lymphoid cell lineage |
15 |
| Regulation of age-associated B cells by IRF5 in systemic autoimmunity |
15 |
| Molecular mechanisms of lineage decisions in metabolite-specific T cells |
15 |
| Altered differentiation is central to HIV-specific CD4(+) T cell dysfunction in progressive disease |
15 |
| Monomeric TCRs drive T cell antigen recognition |
15 |
| A TCR mechanotransduction signaling loop induces negative selection in the thymus |
14 |
| BCR affinity differentially regulates colonization of the subepithelial dome and infiltration into germinal centers within Peyer's patches |
14 |
| IL-17-receptor-associated adaptor Acti directly stabilizes mRNAs to mediate IL-17 inflammatory signaling |
14 |
| A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44 |
14 |
| Metabolic exhaustion in infection, cancer and autoimmunity |
14 |
| Resistance of HIV-infected macrophages to CD8(+) T lymphocyte-mediated killing drives activation of the immune system |
14 |
| Flip the coin: IL-7 and IL-7R in health and disease |
14 |
| TSLP: from allergy to cancer |
14 |
| SERPINB1-mediated checkpoint of inflammatory caspase activation |
14 |
| CD8(+) T cells induce cachexia during chronic viral infection |
14 |
| Astrocytes decrease adult neurogenesis during virus-induced memory dysfunction via IL-1 |
13 |
| Atherogenic dyslipidemia promotes autoimmune follicular helper T cell responses via IL-27 |
13 |
| TCRs are randomly distributed on the plasma membrane of resting antigen-experienced T cells |
13 |
| PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing |
13 |
| Arginine methylation controls the strength of gamma c-family cytokine signaling in T cell maintenance |
13 |
| Bcl11b sets pro-T cell fate by site-specific cofactor recruitment and by repressing Id2 and Zbtb16 |
13 |
| Transcription factor Foxp1 regulates Foxp3 chromatin binding and coordinates regulatory T cell function |
13 |
| Locally instructed CXCR4(hi) neutrophils trigger environment-driven allergic asthma through the release of neutrophil extracellular traps |
12 |
| Autocrine-paracrine prostaglandin E-2 signaling restricts TLR4 internalization and TRIF signaling |
12 |
| IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival |
12 |
| A protective Zika virus E-dimer-based subunit vaccine engineered to abrogate antibody-dependent enhancement of dengue infection |
12 |
| Hyperactivated PI3K delta promotes self and commensal reactivity at the expense of optimal humoral immunity |
12 |
| Semaphorin 6D reverse signaling controls macrophage lipid metabolism and anti-inflammatory polarization |
12 |
| Bhlhe40 mediates tissue-specific control of macrophage proliferation in homeostasis and type 2 immunity |
12 |
| RNA-binding protein isoforms ZAP-S and ZAP-L have distinct antiviral and immune resolution functions |
11 |
| IL-9 receptor signaling in memory B cells regulates humoral recall responses |
11 |
| Toll-like receptors TLR2 and TLR4 block the replication of pancreatic beta cells in diet-induced obesity |
11 |
| Approaches and advances in the genetic causes of autoimmune disease and their implications |
11 |
| Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT |
11 |
| Maintenance of CD4 T cell fitness through regulation of Foxo1 |
11 |
| SLAM receptors foster iNKT cell development by reducing TCR signal strength after positive selection |
11 |
| Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity |
11 |
| Transcription-factor-mediated supervision of global genome architecture maintains B cell identity |
11 |
| IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease |
11 |
| The E3 ubiquitin ligase SPOP controls resolution of systemic inflammation by triggering MYD88 degradation |
11 |
| The macrophage tetraspan MS4A4A enhances dectin-1-dependent NK cell-mediated resistance to metastasis |
11 |
| Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity |
11 |
| Activated beta-catenin in Foxp3(+) regulatory T cells links inflammatory environments to autoimmunity |
11 |
| Basophil-derived tumor necrosis factor can enhance survival in a sepsis model in mice |
11 |
| Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis |
11 |
| Uncoupling protein 2 reprograms the tumor microenvironment to support the anti-tumor immune cycle |
11 |
| Nuclear RNF2 inhibits interferon function by promoting K33-linked STAT1 disassociation from DNA |
10 |
| Identification of a novel arthritis-associated osteoclast precursor macrophage regulated by FoxM1 |
10 |
| TCR sequencing paired with massively parallel 3 ' RNA-seq reveals clonotypic T cell signatures |
10 |
| Combating herpesvirus encephalitis by potentiating a TLR3-mTORC2 axis |
10 |
| Sex-hormone-driven innate antibodies protect females and infants against EPEC infection |
10 |
