Neurobiology Of Disease

Neurobiology Of Disease

疾病神经生物学

  • 2区 中科院分区
  • Q1 JCR分区

高引用文章

文章名称 引用次数
Alpha-synuclein: Pathology, mitochondrial dysfunction and neuroinflammation in Parkinson's disease 69
The olfactory bulb as the entry site for prion-like propagation in neurodegenerative diseases 44
Lysosome trafficking and signaling in health and neurodegenerative diseases 33
Selective NLRP3 inflammasome inhibitor reduces neuroinflammation and improves long-term neurological outcomes in a murine model of traumatic updates brain injury 32
Epilepsy biomarkers - Toward etiology and pathology specificity 27
Mechanisms of selective autophagy and mitophagy: Implications for neurodegenerative diseases 24
Distinct alpha-Synuclein strains and implications for heterogeneity among alpha-Synucleinopathies 23
Targeting PERK signaling with the small molecule GSK2606414 prevents neurodegeneration in a model of Parkinson's disease 22
Neuromodulation targets pathological not physiological beta bursts during gait in Parkinson's disease 22
Alterations in cortical interneurons and cognitive function in schizophrenia 22
Familial knockin mutation of LRRK2 causes lysosomal dysfunction and accumulation of endogenous insoluble alpha-synuclein in neurons 21
Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology 20
Pathogenesis and pathophysiology of functional (psychogenic) movement disorders 20
Autophagy and mitophagy in ALS 20
TFEB dysregulation as a driver of autophagy dysfunction in neurodegenerative disease: Molecular mechanisms, cellular processes, and emerging therapeutic opportunities 20
Translation-relevant EEG phenotypes in a mouse Syndrome 19
Beta bursts during continuous movements accompany the velocity decrement in Parkinson's disease patients 18
Prion-like seeding and nucleation of intracellular amyloid-beta 17
Development of an aggregate-selective, human-derived alpha-synuclein antibody BIIB054 that ameliorates disease phenotypes in Parkinson's disease models 17
Beneficial effects of n-3 polyunsaturated fatty acids administration in a partial lesion model of Parkinson's disease: The role of glia and NRf2 regulation 17
The role of monogenic genes in idiopathic Parkinson's disease 16
Beta burst coupling across the motor circuit in Parkinson's disease 16
Roles for neuronal and glial autophagy in synaptic pruning during development 16
Aging, lifestyle and dementia 15
Distinct cytokine profiles in human brains resilient to Alzheimer's pathology 15
Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease 15
Status epilepticus triggers long-lasting activation of complement C1q-C3 signaling in the hippocampus that correlates with seizure frequency in experimental epilepsy 15
Affective, neurocognitive and psychosocial disorders associated with traumatic brain injury and post-traumatic epilepsy 14
A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility 14
Decline in Sirtuin-1 expression and activity plays a critical role in blood-brain barrier permeability in aging 14
RNA sequencing reveals MMP2 and TGFB1 downregulation in LRRK2 G2019S Parkinson's iPSC-derived astrocytes 14
Mitochondria and neuroprotection in stroke: Cationic arginine-rich peptides (CARPs) as a novel class of mitochondria-targeted neuroprotective therapeutics 14
Internalization, axonal transport and release of fibrillar forms of alpha-synuclein 14
Organophosphate pesticide chlorpyrifos impairs STAT1 signaling to induce dopaminergic neurotoxicity: Implications for mitochondria mediated oxidative stress signaling events 14
A role for autophagy in Huntington's disease 14
Emerging roles of extracellular vesicles in neurodegenerative disorders 13
Axl activation attenuates neuroinflammation by inhibiting the TLR/TRAF/NF-kappa B pathway after MCAO in rats 13
Synchronised spiking activity underlies phase amplitude coupling in the subthalamic nucleus of Parkinson's disease patients 13
Following spinal cord injury, PDE4B drives an acute, local inflammatory response and a chronic, systemic response exacerbated by gut dysbiosis and endotoxemia 13
Neurotoxic astrocytes express the D-serine synthesizing enzyme, serine racemase, in Alzheimer's disease 13
Gallic acid disruption of A beta(1-42) aggregation rescues cognitive decline of APP/PS1 double transgenic mouse 12
Preclinical development of a high affinity alpha-synuclein antibody, MEDI that can enter the brain, sequester extracellular alpha-synuclein and attenuate alpha-synuclein spreading in vivo 12
Age-dependent neurodegeneration and organelle transport deficiencies in mutant TDP43 patient-derived neurons are independent of TDP43 aggregation 12
Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor dysfunction 12
Novel E815K knock-in mouse model of alternating hemiplegia of childhood 12
A beta propagation and strains: Implications for the phenotypic diversity in Alzheimer's disease 12
Neuronal pentraxin 1: A synaptic-derived plasma biomarker in Alzheimer's disease 12
Bexarotene protects against neurotoxicity partially through a PPAR gamma-dependent mechanism in mice following traumatic brain injury 12
Poly-ubiquitin profile in Alzheimer disease brain 12
Does inflammation precede tau aggregation in early Alzheimer's disease? A PET study 12