| Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study |
141 |
| Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease |
114 |
| Circular RNAs: Promising Biomarkers for Human Diseases |
94 |
| Fisetin is a senotherapeutic that extends health and lifespan |
76 |
| Long noncoding RNA PCAT6 functions as an oncogene by binding to EZH2 and suppressing LATS2 in non-small-cell lung cancer |
46 |
| Three isoforms of exosomal circPTGR1 promote hepatocellular carcinoma metastasis via the miR449a-MET pathway |
42 |
| Deep Convolutional Neural Networks Enable Discrimination of Heterogeneous Digital Pathology Images |
42 |
| Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs |
41 |
| Obesity and Cancer: Existing and New Hypotheses for a Causal Connection |
41 |
| Cancer-associated fibroblasts contribute to oral cancer cells proliferation and metastasis via exosome-mediated paracrine miR-34a-5p |
40 |
| Development and validation of a TP53-associated immune prognostic model for hepatocellular carcinoma |
40 |
| Sodium Butyrate Inhibits Inflammation and Maintains Epithelium Barrier Integrity in a TNBS-induced Inflammatory Bowel Disease Mice Model |
39 |
| Modified Mediterranean-ketogenic diet modulates gut microbiome and short-chain fatty acids in association with Alzheimer's disease markers in subjects with mild cognitive impairment |
39 |
| Traumatic Brain Injury and Alzheimer's Disease: The Cerebrovascular Link |
37 |
| The circRNA circPTPRA suppresses epithelial-mesenchymal transitioning and metastasis of NSCLC cells by sponging miR-96-5p |
36 |
| Exosomal miRNA confers chemo resistance via targeting Cav1/p-gp/M2-type macrophage axis in ovarian cancer |
35 |
| In Vitro Regeneration of Patient-specific Ear-shaped Cartilage and Its First Clinical Application for Auricular Reconstruction |
34 |
| AMSC-derived exosomes alleviate lipopolysaccharide/D-galactosamine-induced acute liver failure by miR-17-mediated reduction of TXNIP/NLRP3 inflammasome activation in macrophages |
33 |
| Enhanced Immunosuppressive Properties of Human Mesenchymal Stem Cells Primed by Interferon-gamma |
33 |
| Lighting a Fire in the Tumor Microenvironment Using Oncolytic Immunotherapy |
32 |
| Ischemia-Reperfusion Injury Reduces Long Term Renal Graft Survival: Mechanism and Beyond |
30 |
| MALAT1 sponges miR-106b-5p to promote the invasion and metastasis of colorectal cancer via SLAIN2 enhanced microtubules mobility |
29 |
| MiR-873/PD-L1 axis regulates the stemness of breast cancer cells |
29 |
| Epileptic Seizure Prediction Using Big Data and Deep Learning: Toward a Mobile System |
29 |
| Apoptosis-Inducing Factor (AIF) in Physiology and Disease: The Tale of a Repented Natural Born Killer |
29 |
| Comprehensive molecular and immunological characterization of hepatocellular carcinoma |
28 |
| Targeting glutaminase 1 attenuates sternness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway |
28 |
| Profiles of alternative splicing in colorectal cancer and their clinical significance: A study based on large-scale sequencing data |
28 |
| The RNA-binding protein RBM3 promotes cell proliferation in hepatocellular carcinoma by regulating circular RNA SCD-circRNA 2 production |
28 |
| Exosomal transfer of miR-1238 contributes to temozolomide-resistance in glioblastoma |
28 |
| Senolytics and senostatics as adjuvant tumour therapy |
27 |
| Surgery, neuroinflammation and cognitive impairment |
27 |
| KRAS-mutant non-small cell lung cancer: Converging small molecules and immune checkpoint inhibition |
26 |
| Radiomics signature of computed tomography imaging for prediction of survival and chemotherapeutic benefits in gastric cancer |
26 |
| Gut microbiota in Parkinson's disease: Temporal stability and relations to disease progression |
26 |
| PDL1 is expressed in the islets of people with type 1 diabetes and is up-regulated by interferons-alpha and-gamma via IRF1 induction |
25 |
| Neural stem cell derived extracellular vesicles: Attributes and prospects for treating neurodegenerative disorders |
25 |
| Development and Validation of a 28-gene Hypoxia-related Prognostic Signature for Localized Prostate Cancer |
24 |
| Downregulation of circRNA DMNT3B contributes to diabetic retinal vascular dysfunction through targeting miR-20b-5p and BAMBI |
24 |
| Heterologous Two-Dose Vaccination with Simian Adenovirus and Poxvirus Vectors Elicits Long-Lasting Cellular Immunity to Influenza Virus A in Healthy Adults |
24 |
| Boosting mTOR-dependent autophagy via upstream TLR4-MyD88-MAPK signalling and downstream NF-kappa B pathway quenches intestinal inflammation and oxidative stress injury |
24 |
| Development and validation of an immune gene-set based Prognostic signature in ovarian cancer |
23 |
| LncRNA HOTAIR epigenetically suppresses miR-122 expression in hepatocellular carcinoma via DNA methylation |
23 |
| N-6-methyladenosine modification of ITGA6 mRNA promotes the development and progression of bladder cancer |
23 |
| Interferon Gamma Induces Reversible Metabolic Reprogramming of M1 Macrophages to Sustain Cell Viability and Pro-Inflammatory Activity |
22 |
| Skeletal muscle as potential central link between sarcopenia and immune senescence |
22 |
| International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact |
22 |
| Simultaneous blocking of CD47 and PD-L1 increases innate and adaptive cancer immune responses and cytokine release |
21 |
| Systematic Analysis of Survival-Associated Alternative Splicing Signatures in Gastrointestinal Pan-Adenocarcinomas |
21 |
| A genetic association study of glutamine-encoding DNA sequence structures, somatic CAG expansion, and DNA repair gene variants, with Huntington disease clinical outcomes |
21 |
