| Anti-spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection |
264 |
| Comorbid diabetes results in immune dysregulation and enhanced disease severity following MERS-CoV infection |
100 |
| Generation and testing of clinical-grade exosomes for pancreatic cancer |
91 |
| Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation |
84 |
| Maladaptive role of neutrophil extracellular traps in pathogen-induced lung injury |
59 |
| PD-L1 expression and tumor mutational burden are independent biomarkers in most cancers |
54 |
| Interleukin-7 restores lymphocytes in septic shock: the IRIS-7 randomized clinical trial |
52 |
| Brain-wide glymphatic enhancement and clearance in humans assessed with MRI |
49 |
| T cell receptor repertoire features associated with survival in immunotherapy-treated pancreatic ductal adenocarcinoma |
38 |
| Pancreatic cancer therapy with combined mesothelin-redirected chimeric antigen receptor T cells and cytokine-armed oncolytic adenoviruses |
37 |
| Tumor-draining lymph nodes are pivotal in PD-1/PD-L1 checkpoint therapy |
37 |
| Enhanced detection of neoantigen-reactive T cells targeting unique and shared oncogenes for personalized cancer immunotherapy |
37 |
| Tumor-specific MHC-II expression drives a unique pattern of resistance to immunotherapy via LAG-3/FCRL6 engagement |
35 |
| First-in-human topical microbiome transplantation with Roseomonas mucosa for atopic dermatitis |
34 |
| Necroptosis: a crucial pathogenic mediator of human disease |
33 |
| Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma |
33 |
| Clinical implications of monitoring nivolumab immunokinetics in non-small cell lung cancer patients |
32 |
| Randomized trial of intravenous iron-induced hypophosphatemia |
32 |
| A nanoparticle-incorporated STING activator enhances antitumor immunity in PD-L1-insensitive models of triple-negative breast cancer |
32 |
| SGLT2 inhibition reprograms systemic metabolism via FGF21-dependent and -independent mechanisms |
31 |
| Single-cell analysis of fate-mapped macrophages reveals heterogeneity, including stem-like properties, during atherosclerosis progression and regression |
31 |
| Frameshift events predict anti-PD-1/L1 response in head and neck cancer |
31 |
| The evolving relationship of wound healing and tumor stroma |
30 |
| Inhibiting myeloid-derived suppressor cell trafficking enhances T cell immunotherapy |
29 |
| Lipid abnormalities in atopic skin are driven by type 2 cytokines |
29 |
| Continuous treatment with IL-15 exhausts human NK cells via a metabolic defect |
28 |
| The failing heart utilizes 3-hydroxybutyrate as a metabolic stress defense |
27 |
| Neutrophil accumulation and NET release contribute to thrombosis in HIT |
27 |
| Human adipose beiging in response to cold and mirabegron |
26 |
| Intravascular hemolysis activates complement via cell-free heme and heme-loaded microvesicles |
26 |
| Dietary carbohydrate restriction improves metabolic syndrome independent of weight loss |
26 |
| Targeting the gut microbiome to treat the osteoarthritis of obesity |
26 |
| Combining STING-based neoantigen-targeted vaccine with checkpoint modulators enhances antitumor immunity in murine pancreatic cancer |
26 |
| Single-cell RNA sequencing identifies TGF-beta as a key regenerative cue following LPS-induced lung injury |
25 |
| Deep phenotyping of human induced pluripotent stem cell-derived atrial and ventricular cardiomyocytes |
24 |
| Changes in body composition and weight during the menopause transition |
24 |
| Integrating molecular pathogenesis and clinical translation in sepsis-induced acute respiratory distress syndrome |
24 |
| Global immune fingerprinting in glioblastoma patient peripheral blood reveals immune-suppression signatures associated with prognosis |
24 |
| Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution |
23 |
| mTOR pathway activation drives lung cell senescence and emphysema |
23 |
| Signatures of CD8(+) T cell dysfunction in AML patients and their reversibility with response to chemotherapy |
23 |
| Intracellular localization of diacylglycerols and sphingolipids influences insulin sensitivity and mitochondrial function in human skeletal muscle |
23 |
| Tumor cell oxidative metabolism as a barrier to PD-1 blockade immunotherapy in melanoma |
23 |
| Endogenous retrovirus expression is associated with response to immune checkpoint blockade in clear cell renal cell carcinoma |
23 |
| Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk |
23 |
| Exosome-delivered microRNAs promote IFN-alpha secretion by human plasmacytoid DCs via TLR7 |
22 |
| Single cell RNA sequencing identifies unique inflammatory airspace macrophage subsets |
22 |
| Neutrophil subsets and their gene signature associate with vascular inflammation and coronary atherosclerosis in lupus |
22 |
| Mast cells and neutrophils mediate peripheral motor pathway degeneration in ALS |
22 |
| Human PAH is characterized by a pattern of lipid-related insulin resistance |
22 |
