| Controlled drug delivery vehicles for cancer treatment and their performance |
213 |
| Targeting oncogenic Myc as a strategy for cancer treatment |
89 |
| The independence of and associations among apoptosis, autophagy, and necrosis |
67 |
| The emerging treatment landscape of targeted therapy in non-small-cell lung cancer |
61 |
| Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles |
57 |
| Targeting epigenetic regulators for cancer therapy: mechanisms and advances in clinical trials |
53 |
| History and progress of hypotheses and clinical trials for Alzheimer's disease |
49 |
| PROTACs: great opportunities for academia and industry |
41 |
| Targeting EGFR exon 20 insertion mutations in non-small cell lung cancer |
39 |
| The intracellular signalosome of PD-L1 in cancer cells |
35 |
| Genetically engineered T cells for cancer immunotherapy |
31 |
| Targeting IL-2: an unexpected effect in treating immunological diseases |
28 |
| Targeted therapeutic options and future perspectives for HER2-positive breast cancer |
28 |
| Emerging insights into HAUSP (USP7) in physiology, cancer and other diseases |
28 |
| Demystifying the manipulation of host immunity, metabolism, and extraintestinal tumors by the gut microbiome |
24 |
| miRNAs reshape immunity and inflammatory responses in bacterial infection |
23 |
| Yes-associated protein (YAP) in pancreatic cancer: at the epicenter of a targetable signaling network associated with patient survival |
22 |
| A nanomedicine approach enables co-delivery of cyclosporin A and gefitinib to potentiate the therapeutic efficacy in drug-resistant lung cancer |
21 |
| Biological processes and signal transduction pathways regulated by the protein methyltransferase SETD7 and their significance in cancer |
18 |
| DNA-PKcs promotes alcohol-related liver disease by activating Drp1-related mitochondrial fission and repressing FUNDC1-required mitophagy |
17 |
| USP7 deubiquitinates and stabilizes NOTCH1 in T-cell acute lymphoblastic leukemia |
16 |
| Metabolite sensing and signaling in cell metabolism |
16 |
| Transcriptional cofactors Ski and SnoN are major regulators of the TGF-beta/Smad signaling pathway in health and disease |
14 |
| The roles of exosomal miRNAs and lncRNAs in lung diseases |
14 |
| Targeting cell signaling in allergic asthma |
13 |
| RNA-binding protein LIN28B inhibits apoptosis through regulation of the AKT2/FOXO3A/BIM axis in ovarian cancer cells |
13 |
| Targeting growth hormone function: strategies and therapeutic applications |
13 |
| miR-23a promotes invasion of glioblastoma via HOXD10-regulated glial-mesenchymal transition |
12 |
| DNA methylation profile is associated with the osteogenic potential of three distinct human odontogenic stem cells |
12 |
| Targeted chemotherapy for subcutaneous and orthotopic non-small cell lung tumors with cyclic RGD-functionalized and disulfide-crosslinked polymersomal doxorubicin |
12 |
| ReishiMax inhibits mTORC1/2 by activating AMPK and inhibiting IGFR/PI3K/Rheb in tumor cells |
12 |
| Effects of insulin and pathway inhibitors on the PI3K-Akt-mTOR phosphorylation profile in acute myeloid leukemia cells |
11 |
| Local delivery of arsenic trioxide nanoparticles for hepatocellular carcinoma treatment |
11 |
| Increased mtDNA copy number promotes cancer progression by enhancing mitochondrial oxidative phosphorylation in microsatellite-stable colorectal cancer |
10 |
| Integrative analysis of DNA methylation and gene expression identified cervical cancer-specific diagnostic biomarkers |
10 |
| Pazopanib in advanced soft tissue sarcomas |
10 |
| gamma-tubulin as a signal-transducing molecule and meshwork with therapeutic potential |
9 |
| The role of autophagy in colitis-associated colorectal cancer |
9 |
| Novel HDAC5-interacting motifs of Tbx3 are essential for the suppression of E-cadherin expression and for the promotion of metastasis in hepatocellular carcinoma |
9 |
| Loss of mdig expression enhances DNA and histone methylation and metastasis of aggressive breast cancer |
8 |
| Predicting responses to platin chemotherapy agents with biochemically-inspired machine learning |
8 |
| EGFR TKIs impair lysosome-dependent degradation of SQSTM1 to compromise the effectiveness in lung cancer |
7 |
| Chemical compound cinobufotalin potently induces FOXO1-stimulated cisplatin sensitivity by antagonizing its binding partner MYH9 |
7 |
| MKP-1 reduces A beta generation and alleviates cognitive impairments in Alzheimer's disease models |
7 |
| The roles of prostaglandin F-2 in regulating the expression of matrix metalloproteinase-12 via an insulin growth factor-2-dependent mechanism in sheared chondrocytes |
7 |
| Pan-CDK inhibition augments cisplatin lethality in nasopharyngeal carcinoma cell lines and xenograft models |
6 |
| Potent delivery of an MMP inhibitor to the tumor microenvironment with thermosensitive liposomes for the suppression of metastasis and angiogenesis |
6 |
| The dual-inhibitory effect of miR-338-5p on the multidrug resistance and cell growth of hepatocellular carcinoma |
6 |
| Therapeutic effects of a novel BAFF blocker on arthritis |
6 |
| Targeting MUC1-C suppresses BCL2A1 in triple-negative breast cancer |
5 |
| Jumonji domain-containing 6 (JMJD6) identified as a potential therapeutic target in ovarian cancer |
5 |
| E6-induced selective translation of WNT4 and JIP2 promotes the progression of cervical cancer via a noncanonical WNT signaling pathway |
5 |
| ETV2 mediates endothelial transdifferentiation of glioblastoma |
4 |
| Deciphering the regulatory and catalytic mechanisms of an unusual SAM-dependent enzyme |
4 |
| Saikosaponin D suppresses enterovirus A71 infection by inhibiting autophagy |
4 |
| Dickkopf-1 contributes to hepatocellular carcinoma tumorigenesis by activating the Wnt/beta-catenin signaling pathway |
3 |
| TGIF2 promotes the progression of lung adenocarcinoma by bridging EGFR/RAS/ERK signaling to cancer cell stemness |
3 |
| Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence |
3 |
| Peptides encoded by noncoding genes: challenges and perspectives |
2 |
| The beta-catenin/YAP signaling axis is a key regulator of melanoma-associated fibroblasts |
2 |
| The interrelationship between cerebral ischemic stroke and glioma: a comprehensive study of recent reports |
2 |
| Tumor-suppressive function and mechanism of HOXB13 in right-sided colon cancer |
2 |
| PCDH17 increases the sensitivity of colorectal cancer to 5-fluorouracil treatment by inducing apoptosis and autophagic cell death |
2 |
| Counterbalance: modulation of VEGF/VEGFR activities by TNFSF15 |
2 |
| TdIF1: a putative oncogene in NSCLC tumor progression |
2 |
| Epigenetic drug library screening identified an LSD1 inhibitor to target UTX-deficient cells for differentiation therapy |
2 |
| Detection of PRMT1 inhibitors with stopped flow fluorescence |
2 |
| The proatherosclerotic function of indoleamine 3-dioxygenase 1 in the developmental stage of atherosclerosis |
1 |
| Global profiling of O-GlcNAcylated and/or phosphorylated proteins in hepatoblastoma |
1 |
| Structural basis for the acetylation of histone H3K9 and H3K27 mediated by the histone chaperone Vps75 in Pneumocystis carinii |
1 |
| Targeting the insulin-like growth factor-1 receptor in MTAP-deficient renal cell carcinoma |
1 |
| Signal-induced PARP1-Erk synergism mediates IEG expression |
1 |
| miR-124/VAMP3 is a novel therapeutic target for mitigation of surgical trauma-induced microglial activation |
1 |
| Patient-derived orthotopic xenograft models for cancer of unknown primary precisely distinguish chemotherapy, and tumor-targeting S. typhimurium A1-R is superior to first-line chemotherapy |
0 |
| Context-dependent AMPK activation distinctly regulates TAp73 stability and transcriptional activity |
0 |
