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Longitudinal multimorbidity trajectories shape personalized glycaemic pattern
Author: Zhang, Ke; Chen, Jieteng; Yan, Yan; Wang, Huijun; Miao, Zelei; Gou, Wanglong; Xiao, Congmei; Shi, Ruiqi; Jia, Xiaofang; Du, Wenwen; Huang, Yujing; Guo, Tiannan; Su, Chang; Fu, Yuanqing; Chen, Yu-ming; Zheng, Ju-Sheng
Journal: NATURE METABOLISM. 2026; Vol. , Issue , pp. -. DOI: 10.1038/s42255-026-01512-0
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Early-activated extracellular matrix proteins shape the metabolic and spatial dynamics of the kidney fibrotic microenvironmen
Author: Gui, Yuan; Li, Wenxue; Liu, Jia-Jun; Wang, Yuanyuan; Jones, Cameron; Bansal, Riddhi; Mallari, Samantha Mae; Shaffer, Henry Wells; Yu, Yanbao; Fu, Haiyan; Tang, Tracy T.; Liu, Silvia; Liu, Yansheng; Zhou, Dong
Journal: NATURE METABOLISM. 2026; Vol. 8, Issue 3, pp. -. DOI: 10.1038/s42255-026-01458-3
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Extracellular CD44 lactylation impairs CD8+ T cell function in KRAS-mutant colorectal cance
Author: Yang, Yun; Wu, Yong; Guo, Xin; Gan, Wen-Juan; Wu, Wen-Xin; Shi, Wei-Yi; He, Xiao-Shun; Liu, Yi-Xuan; Wan, Shan; Jiang, Zhi; Liu, Yue; Li, Xiu-Ming; Pan, Zu-Da; Zhang, Xue; Xu, You; Gao, Xiao-Jiao; Guo, Ling-Chuan; Li, Guideng; Wu, Hua
Journal: NATURE METABOLISM. 2026; Vol. , Issue , pp. -. DOI: 10.1038/s42255-026-01482-3
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Lipid-dependent accrual of a subset of monocyte-derived macrophages is essential for tissue regeneratio
Author: Yao, Tao; Tian, Xin; Rao, Linbin; Ni, Jinling; Yu, Jiayong; Yang, Hongguo; Tang, Yuexiao; Huang, Xingxiao; Xia, Xintong; Zhao, Lin; Diao, Bowen; Ping, Yan; Wei, Danni; Li, Siqi; Chai, Hui; Hu, Zhiming; Ruan, Xiongzhong; Feng, Suihan; Shao, Mengle; Shan, Bo; Wu, Ying
Journal: NATURE METABOLISM. 2026; Vol. 8, Issue 3, pp. -. DOI: 10.1038/s42255-026-01480-5
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DGAT1 mediates sex-specific CD8+ T cell antitumour response
Author: Madi, Alaa; Shi, Hui; Su, Min; Mady, Ahmed; Lv, Boqiong; Wang, Haiyan; Yang, Bing; Yan, Zhenni; Jin, Xiaomeng; Wu, Lingling; Lv, Mengyue; Hering, Marvin; Ma, Sicong; Mieg, Alessa; Zettl, Ferdinand; Yan, Xin; Mohr, Kerstin; Knabe, Nora; Poschet, Gernot; Richter, Karsten; Schleussner, Nikolai; Jackstadt, Rene-Filip; Loges, Sonja; Papavasiliou, F. Nina; Wang, Xi; Wu, Jingxia; Cui, Guoliang
Journal: NATURE METABOLISM. 2026; Vol. 8, Issue 3, pp. -. DOI: 10.1038/s42255-026-01462-7
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Unravelling the molecular mechanisms causal to type 2 diabetes across global populations and disease-relevant tissue
Author: Bocher, Ozvan; Arruda, Ana Luiza; Yoshiji, Satoshi; Zhao, Chi; Huerta-Chagoya, Alicia; Su, Chen-Yang; Yin, Xianyong; Cammann, Davis; Taylor, Henry J.; Chen, Jingchun; Suzuki, Ken; Mandla, Ravi; Yang, Ta-Yu; Matsuda, Fumihiko; Mercader, Josep M.; Flannick, Jason; Meigs, James B.; Wood, Alexis C.; Vujkovic, Marijana; Voight, Benjamin F.; Spracklen, Cassandra N.; Rotter, Jerome I.; Morris, Andrew P.; Zeggini, Eleftheria
Journal: NATURE METABOLISM. 2026; Vol. , Issue , pp. -. DOI: 10.1038/s42255-025-01444-1
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Mitochondrial superoxide regulates nuclear envelope integrity and ageing via redox-mediated lipid metabolis
Author: Chen, Peng X.; Zhang, Leyuan; Wu, Xueying; Liang, Zhiqiang; Hao, Xusheng; Zhu, Qingyuan; Liu, Ying; Zheng, Jinrou; Zhang, Qian; Yang, Qinmeng; Zhou, Fan; Zhou, Chunbao; Tian, Ye
Journal: NATURE METABOLISM. 2026; Vol. , Issue , pp. -. DOI: 10.1038/s42255-026-01452-9
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Feeding-regulated glycogen metabolism drives rhythmic liver protein secretio
Author: Weger, Meltem; Mauvoisin, Daniel; Hoyle, Dominic; Wang, Jingkui; Martin, Eva; Rae, James; Ferguson, Charles; Klinke, Glynis; Cielesh, Michelle; Macauslane, Kyle L.; Larance, Mark; Quadroni, Manfredo; Templeman, Iain; Walhin, Jean-Philippe; Karagounis, Leonidas G.; Betts, James A.; Johnston, Jonathan D.; Durussel, Fanny; Firsov, Dmitri; Fournier, Stephane; Muller, Olivier; Schulz, Benjamin L.; Parton, Robert G.; Weger, Benjamin D.; Gachon, Frederic
Journal: NATURE METABOLISM. 2026; Vol. , Issue , pp. -. DOI: 10.1038/s42255-026-01453-8
