| Coupling Krebs cycle metabolites to signalling in immunity and cancer |
59 |
| The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans |
49 |
| Microbial regulation of organismal energy homeostasis |
44 |
| Metabolic signatures of cancer cells and stem cells |
37 |
| A network of trans-cortical capillaries as mainstay for blood circulation in long bones |
37 |
| Cardiac glycosides are broad-spectrum senolytics |
36 |
| Slc12a8 is a nicotinamide mononucleotide transporter |
29 |
| Characterization of hypoxia-associated molecular features to aid hypoxia-targeted therapy |
29 |
| Metabolic regulation of dermal fibroblasts contributes to skin extracellular matrix homeostasis and fibrosis |
26 |
| Mitochondrial complex III is necessary for endothelial cell proliferation during angiogenesis |
26 |
| NADPH production by the oxidative pentose-phosphate pathway supports folate metabolism |
25 |
| The long noncoding RNA CHROME regulates cholesterol homeostasis in primates |
24 |
| Ablation of adipocyte creatine transport impairs thermogenesis and causes diet-induced obesity |
23 |
| Leptin and the endocrine control of energy balance |
23 |
| TGF-beta 2 is an exercise-induced adipokine that regulates glucose and fatty acid metabolism |
21 |
| AMPK activation protects against diet-induced obesity through Ucp1-independent thermogenesis in subcutaneous white adipose tissue |
20 |
| Molecular logic of mTORC1 signalling as a metabolic rheostat |
20 |
| Branched-chain amino acids impact health and lifespan indirectly via amino acid balance and appetite control |
20 |
| Mitochondrial pyruvate import is a metabolic vulnerability in androgen receptor-driven prostate cancer |
20 |
| Metabolic adaptation and maladaptation in adipose tissue |
18 |
| Nrf2 controls iron homoeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin |
18 |
| Human brown adipose tissue is phenocopied by classical brown adipose tissue in physiologically humanized mice |
18 |
| Cellular redox state constrains serine synthesis and nucleotide production to impact cell proliferation |
17 |
| Endothelial TGF-beta signalling drives vascular inflammation and atherosclerosis |
17 |
| m(6)A mRNA methylation regulates human beta-cell biology in physiological states and in type 2 diabetes |
17 |
| Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation |
17 |
| Astrocytic mitochondrial ROS modulate brain metabolism and mouse behaviour |
17 |
| Dynamic interactions of ABHD5 with PNPLA3 regulate triacylglycerol metabolism in brown adipocytes |
16 |
| Two-stage metabolic remodelling in macrophages in response to lipopolysaccharide and interferon-gamma stimulation |
15 |
| Voltage-energized calcium-sensitive ATP production by mitochondria |
15 |
| Transcriptional network analysis implicates altered hepatic immune function in NASH development and resolution |
14 |
| Synergistic substrate cofeeding stimulates reductive metabolism |
14 |
| Metabolic Messengers: adiponectin |
14 |
| An upper limit on Gibbs energy dissipation governs cellular metabolism |
14 |
| Leader beta-cells coordinate Ca2+ dynamics across pancreatic islets in vivo |
13 |
| MANF regulates metabolic and immune homeostasis in ageing and protects against liver damage |
13 |
| Liver macrophages regulate systemic metabolism through non-inflammatory factors |
12 |
| Metformin-induced increases in GDF15 are important for suppressing appetite and promoting weight loss |
12 |
| Transferrin receptor 2 controls bone mass and pathological bone formation via BMP and Wnt signalling |
12 |
| Spatial sorting enables comprehensive characterization of liver zonation |
12 |
| Metabolic plasticity of HIV-specific CD8(+) T cells is associated with enhanced antiviral potential and natural control of HIV-1 infection |
12 |
| The lipid-droplet-associated protein ABHD5 protects the heart through proteolysis of HDAC4 |
11 |
| Inter-organ cross-talk in metabolic syndrome |
11 |
| Defects in mtDNA replication challenge nuclear genome stability through nucleotide depletion and provide a unifying mechanism for mouse progerias |
11 |
| miR-147b-mediated TCA cycle dysfunction and pseudohypoxia initiate drug tolerance to EGFR inhibitors in lung adenocarcinoma |
11 |
| A nutritional memory effect counteracts the benefits of dietary restriction in old mice |
9 |
| Glutamine independence is a selectable feature of pluripotent stem cells |
9 |
| Increased beta-cell proliferation before immune cell invasion prevents progression of type 1 diabetes |
9 |
| Olfaction regulates organismal proteostasis and longevity via microRNA-dependent signalling |
9 |
| The hepatokine Tsukushi gates energy expenditure via brown fat sympathetic innervation |
8 |
