| MAFFT online service: multiple sequence alignment, interactive sequence choice and visualization |
622 |
| Deep learning for healthcare: review, opportunities and challenges |
160 |
| Gene co-expression analysis for functional classification and gene-disease predictions |
111 |
| BioSeq-Analysis: a platform for DNA, RNA and protein sequence analysis based on machine learning approaches |
81 |
| MicroRNAs and complex diseases: from experimental results to computational models |
73 |
| Circular RNA identification based on multiple seed matching |
67 |
| Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences |
57 |
| The BioCyc collection of microbial genomes and metabolic pathways |
44 |
| A review on machine learning principles for multi-view biological data integration |
42 |
| A review of methods and databases for metagenomic classification and assembly |
41 |
| MetSigDis: a manually curated resource for the metabolic signatures of diseases |
36 |
| Evaluation of variable selection methods for random forests and omics data sets |
33 |
| iProt-Sub: a comprehensive package for accurately mapping and predicting protease-specific substrates and cleavage sites |
32 |
| A systematic evaluation of normalization methods in quantitative label-free proteomics |
31 |
| Computational pan-genomics: status, promises and challenges |
29 |
| Function determinants of TET proteins: the arrangements of sequence motifs with specific codes |
27 |
| Recent applications of deep learning and machine intelligence on in silico drug discovery: methods, tools and databases |
27 |
| Selecting between-sample RNA-Seq normalization methods from the perspective of their assumptions |
25 |
| Sixty-five years of the long march in protein secondary structure prediction: the final stretch? |
23 |
| Nanopore sequencing technology and tools for genome assembly: computational analysis of the current state, bottlenecks and future directions |
23 |
| A review of connectivity map and computational approaches in pharmacogenomics |
21 |
| Computational prediction of drug-target interactions using chemogenomic approaches: an empirical survey |
21 |
| Microarray is an efficient tool for circRNA profiling |
21 |
| Long noncoding RNA: a crosslink in biological regulatory network |
20 |
| A review of network-based approaches to drug repositioning |
19 |
| In silico polypharmacology of natural products |
19 |
| Network approaches to systems biology analysis of complex disease: integrative methods for multi-omics data |
19 |
| The small peptide world in long noncoding RNAs |
19 |
| Analysis of long noncoding RNAs highlights region-specific altered expression patterns and diagnostic roles in Alzheimer's disease |
18 |
| Large-scale comparative assessment of computational predictors for lysine post-translational modification sites |
18 |
| Mathematical modeling and computational prediction of cancer drug resistance |
18 |
| A comprehensive review and comparison of different computational methods for protein remote homology detection |
17 |
| LncFinder: an integrated platform for long non-coding RNA identification utilizing sequence intrinsic composition, structural information and physicochemical property |
17 |
| Twenty years of bioinformatics research for protease-specific substrate and cleavage site prediction: a comprehensive revisit and benchmarking of existing methods |
17 |
| Computational analysis and prediction of lysine malonylation sites by exploiting informative features in an integrative machine-learning framework |
17 |
| A comprehensive review and comparison of existing computational methods for intrinsically disordered protein and region prediction |
16 |
| The present and future of de novo whole-genome assembly |
16 |
| Comprehensive evaluation of non-hybrid genome assembly tools for third-generation PacBio long-read sequence data |
16 |
| A comprehensive evaluation of popular proteomics software workflows for label-free proteome quantification and imputation |
16 |
| VRprofile: gene-cluster-detection-based profiling of virulence and antibiotic resistance traits encoded within genome sequences of pathogenic bacteria |
15 |
| Nanopore sequencing data analysis: state of the art, applications and challenges |
15 |
| Microbial genomic island discovery, visualization and analysis |
14 |
| Detection of drug-drug interactions through data mining studies using clinical sources, scientific literature and social media |
14 |
| High-throughput sequencing of the T-cell receptor repertoire: pitfalls and opportunities |
14 |
| A global perspective on evolving bioinformatics and data science training needs |
14 |
| Genome-wide characterization of lncRNAs in acute myeloid leukemia |
14 |
| SmProt: a database of small proteins encoded by annotated coding and non-coding RNA loci |
14 |
| Comprehensive review and empirical analysis of hallmarks of DNA RNA- and protein-binding residues in protein chains |
13 |
| Comparative analysis of differential gene expression tools for RNA sequencing time course data |
12 |
| Review of applications of high-throughput sequencing in personalized medicine: barriers and facilitators of future progress in research and clinical application |
12 |
