| Proteolysis targeting chimeras (PROTACs) in 'beyond rule-of-five' chemical space: Recent progress and future challenges |
36 |
| N-Acylhydrazones as drugs |
34 |
| Cyclin dependent kinase (CDK) inhibitors as anticancer drugs: Recent advances (2015-2019) |
32 |
| Vinca alkaloids and analogues as anti-cancer agents: Looking back, peering ahead |
29 |
| Recent encounters with atropisomerism in drug discovery |
28 |
| Development of the first small molecule histone deacetylase 6 (HDAC6) degraders |
27 |
| Sulfonamide derivatives as multi-target agents for complex diseases |
22 |
| Selective degradation of CDK6 by a palbociclib based PROTAC |
22 |
| New approaches for the treatment of Alzheimer's disease |
19 |
| Discovery of the pan-genotypic hepatitis C virus NS3/4A protease inhibitor voxilaprevir (GS-9857): A component of Vosevi (R) |
16 |
| Doxycycline, salinomycin, monensin and ivermectin repositioned as cancer drugs |
14 |
| MF- a novel promising arylpiperazine-hydantoin based 5-HT7 receptor antagonist: In vitro drug-likeness studies and in vivo pharmacological evaluation |
14 |
| Synthesis of 4-triazole-linked urea/thiourea conjugates as cytotoxic and apoptosis inducing agents |
14 |
| Antiviral properties and interaction of novel chalcone derivatives containing a purine and benzenesulfonamide moiety |
14 |
| Thiazolyl-pyrazole derivatives as potential antimycobacterial agents |
14 |
| Discovery of new quinazoline derivatives as irreversible dual EGFR/HER2 inhibitors and their anticancer activities - Part 1 |
13 |
| Pyrazolo[4-d]pyrimidine derivatives containing a Schiff base moiety as potential antiviral agents |
13 |
| Design, synthesis and antifungal evaluation of novel pyrazole carboxamides with diarylamines scaffold as potent succinate dehydrogenase inhibitors |
13 |
| Selective inhibition of monoamine oxidase A by hispidol |
13 |
| Novel amide derivatives containing 4-thiadiazole moiety: Design, synthesis, nematocidal and antibacterial activities |
12 |
| Synthesis, biological evaluation and molecular modeling of a novel series of fused 3-triazoles as potential anti-coronavirus agents |
12 |
| New butenolide derivatives from the marine sponge-derived fungus Aspergillus terreus |
12 |
| Biocompatible G-Quadruplex/BODIPY assembly for cancer cell imaging and the attenuation of mitochondria |
11 |
| Isolation, structural elucidation, and insights into the anti-inflammatory effects of triterpene saponins from the leaves of Stauntonia hexaphylla |
11 |
| Fragment splicing-based design, synthesis and safener activity of novel substituted phenyl oxazole derivatives |
11 |
| Synthesis, antituberculosis studies and biological evaluation of new quinoline derivatives carrying 4-oxadiazole moiety |
11 |
| Inhibition of the LOX enzyme family members with old and new ligands. Selectivity analysis revisited |
11 |
| Recent applications of machine learning in medicinal chemistry |
11 |
| The development of myeloperoxidase inhibitors |
10 |
| Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy |
10 |
| Synthesis of new coumarin tethered isoxazolines as potential anticancer agents |
10 |
| New evolutions in the BACE1 inhibitor field from 2014 to 2018 |
10 |
| Profiling interactions of vaborbactam with metallo-beta-lactamases |
10 |
| MicroRNAs, intestinal inflammatory and tumor |
10 |
| Design, synthesis, and biological evaluation of novel pyrrolo[2-a]pyrazine derivatives |
10 |
| Quantitative structure-activity relationship analysis using deep learning based on a novel molecular image input technique |
10 |
| Synthesis, in vitro alpha-glucosidase inhibitory activity and docking studies of novel chromone-isatin derivatives |
10 |
| Na(v)1.7 inhibitors for the treatment of chronic pain |
10 |
| Azoalkyl ether imidazo[1-b]benzothiazoles as potentially antimicrobial agents with novel structural skeleton |
10 |
| Structure-based design of potent linear peptide inhibitors of the YAP-TEAD protein-protein interaction derived from the YAP omega-loop sequence |
10 |
| A cascade synthesis, in vitro cholinesterases inhibitory activity and docking studies of novel Tacrine-pyranopyrazole derivatives |
10 |
| Synthesis and evaluation of novel substituted 3-triazolyldihydroquinolines as promising antitubercular agents |
10 |
| Highly potent activity of isopulegol-derived substituted octahydro-2H-chromen-4-ols against influenza A and B viruses |
10 |
| Synthesis, characterization and cytotoxicity studies of 3-triazoles and 4-triazolo [5-a] pyrimidines in human breast cancer cells |
9 |
| Chemistry and biology of ophiobolin A and its congeners |
9 |
| Target ROS to induce apoptosis and cell cycle arrest by 7-dimethoxy-4-naphthoquinone derivative |
9 |
| Carbazole-containing amides and ureas: Discovery of cryptochrome modulators as antihyperglycemic agents |
9 |
| Inducing protein-protein interactions with molecular glues |
9 |
| Hit discovery of Mycobacterium tuberculosis inosine 5'-monophosphate dehydrogenase, GuaB inhibitors |
9 |
| An update on sphingosine-1-phosphate receptor 1 modulators |
9 |
