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Discovery of novel 1,2,4-triazoles derivatives acting as NF1 activators against cervical cance
Author: Yin, Yao; Song, Zhibing; Wang, Luqi; Karam, Sami; Zhang, Yijing; Margetic, Davor; Chen, Peiran; Peng, Yingyuan; Yan, Yijia; Chen, Zhi-Long
Journal: BIOORGANIC & MEDICINAL CHEMISTRY. 2026; Vol. 138, Issue , pp. -. DOI: 10.1016/j.bmc.2026.118661
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Synthesis and pharmacological evaluation of benzimidazole amine derivatives as novel allosteric antagonists for β2-adrenergic recepto
Author: Chen, Yu; Ye, Kexin; Zhang, Yujie; Shen, Xinyan; Hou, Yanan; Zhao, Shuai; Miao, Chunbao; Qian, Mingcheng; Chen, Xin
Journal: BIOORGANIC & MEDICINAL CHEMISTRY. 2026; Vol. 138, Issue , pp. -. DOI: 10.1016/j.bmc.2026.118644
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A general tyrosinase-responsive prodrug strategy: design and synthesis of melanoma-selective anticancer agent
Author: Qiu, Boxiang; Zou, Yening; Li, Binjie; Tan, Zhenlulu; Wu, Yongsheng; Zheng, Guojun
Journal: BIOORGANIC & MEDICINAL CHEMISTRY. 2026; Vol. 138, Issue , pp. -. DOI: 10.1016/j.bmc.2026.118648
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Development of Thieno[2,3-b]pyridin-6(7H)-one derivatives against drug-resistant Mycobacterium tuberculosi
Author: Zha, Qin; Liu, Zhiyong; Li, Wanwen; Zhou, Yihuan; McNeil, Matthew B.; Cook, Gregory M.; Zhang, Tianyu; Zhang, Niuniu
Journal: BIOORGANIC & MEDICINAL CHEMISTRY. 2026; Vol. 138, Issue , pp. -. DOI: 10.1016/j.bmc.2026.118663
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Exploring the potential of heterocyclic-containing tail approach in the development of novel covalent inhibitors dual-targeting EGFR and HER-2: design, synthesis and biological evaluatio
Author: Hao, Shuang; Yan, Jing-han; Wang, Rui; Ge, Gong-hui; Si, Meng-chen; Niu, Yi-fan; Cai, Zheng-hao; Zheng, Wei-xin; Zhao, Chen-guang; Li, Xin; Cai, Shuang; Zhang, Ting-jian; Meng, Fan-hao
Journal: BIOORGANIC & MEDICINAL CHEMISTRY. 2026; Vol. 137, Issue , pp. -. DOI: 10.1016/j.bmc.2026.118637
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Hydrocarbon stapling strategy and antitumor activity of antimicrobial peptide Lasioglossum II
Author: Li, Jinqiu; Zhu, Jiayi; Wei, Xinhao; Zhu, Yaojin; Xu, Jingfei; Gao, Fei; Hu, Honggang; He, Shipeng
Journal: BIOORGANIC & MEDICINAL CHEMISTRY. 2026; Vol. 137, Issue , pp. -. DOI: 10.1016/j.bmc.2026.118639
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A multifunctional hydrogel for synergistic dendritic cell activation and immunogenic cell death induction in enhanced chemoimmunotherap
Author: An, Xiaohang; Yan, Wenwen; Wang, Yaqi; Chernikov, Oleg; Li, Ying; Yang, Junjie; Mizgina, Tatiana; Chen, Yue; Cheng, Yige; Jia, Xiangqian
Journal: BIOORGANIC & MEDICINAL CHEMISTRY. 2026; Vol. 137, Issue , pp. -. DOI: 10.1016/j.bmc.2026.118641
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The synthesis and biological evaluation of novel deuterated and non-deuterated aminobenzenesulfonamide derivatives as EGFR inhibito
Author: Hou, Puzhuang; Zhi, Haitao; Cao, Longcai; Qin, Xiaojin; Yao, Han; Ren, Yuanyuan; Jia, Xian; Li, Xingshu
Journal: BIOORGANIC & MEDICINAL CHEMISTRY. 2026; Vol. 137, Issue , pp. -. DOI: 10.1016/j.bmc.2026.118642
