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Design, synthesis and bioactivity evaluations of 8-substituted-quinoli- ne-2-carboxamide derivatives as novel histone deacetylase (HDAC) inhibitors
Author: Zhao, Yunpeng; Yao, Zefu; Ren, Wandi; Yang, Xinying; Hou, Xuben; Cao, Shengda; Fang, Hao
Journal: BIOORGANIC & MEDICINAL CHEMISTRY. 2023; Vol. 85, Issue , pp. -. DOI: 10.1016/j.bmc.2023.117242
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Synthesis and evaluation of sulfonamide derivatives targeting EGFR790M/ L858R mutations and ALK rearrangement as anticancer agents
Author: Cao, Longcai; Yao, Han; Yu, Linlin; Ren, Yuanyuan; Liu, Jiadai; Li, Xingshu; Jia, Xian
Journal: BIOORGANIC & MEDICINAL CHEMISTRY. 2023; Vol. 85, Issue , pp. -. DOI: 10.1016/j.bmc.2023.117241
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SAR study of 1,2-benzisothiazole dioxide compounds that agonize HIF-2 stabilization and EPO production br
Author: Song, Wanbin; Zhuang, Jingjing; Zhang, Nan; Ren, Xintong; Xu, Weiwei; Guo, Mengqi; Diao, Xiaotong; Liu, Chao; Jin, Jiaming; Wu, Dalei; Zhang, Yinan
Journal: BIOORGANIC & MEDICINAL CHEMISTRY. 2023; Vol. 77, Issue , pp. -. DOI: 10.1016/j.bmc.2022.117041
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Development of a spermine lipid for transient antibody expression
Author: Sui, Shaowei; Wang, Hao; Song, Jiajie; Tai, Wanyi
Journal: BIOORGANIC & MEDICINAL CHEMISTRY. 2023; Vol. 78, Issue , pp. -. DOI: 10.1016/j.bmc.2022.117114
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Design, synthesis, and biological evaluation of BRD4 degraders
Author: Ding, Mengyuan; Shao, Yingying; Sun, Danwen; Meng, Suorina; Zang, Yi; Zhou, Yubo; Li, Jia; Lu, Wei; Zhu, Shulei
Journal: BIOORGANIC & MEDICINAL CHEMISTRY. 2023; Vol. 78, Issue , pp. -. DOI: 10.1016/j.bmc.2022.117134
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Neuritogenic steroid glycosides from crown-of-thorns starfish: Possible involvement of p38 mitogen-activated protein kinase and attenuation of cognitive impairment in senescence-accelerated mice (SAMP8) by peripheral administration
Author: Sasayama, Yumi; Mamiya, Takayoshi; Qi, Jianhua; Shibata, Takahiro; Uchida, Koji; Nabeshima, Toshitaka; Ojika, Makoto
Journal: BIOORGANIC & MEDICINAL CHEMISTRY. 2023; Vol. 78, Issue , pp. -. DOI: 10.1016/j.bmc.2022.117144
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Efficient delivery of VEGFA mRNA for promoting wound healing via ionizable lipid nanoparticles
Author: Dong, Shuo; Wang, Ji; Guo, Zongke; Zhang, Yanhao; Zha, Wenhui; Wang, Yang; Liu, Chao; Xing, Hanlei; Li, Xinsong
Journal: BIOORGANIC & MEDICINAL CHEMISTRY. 2023; Vol. 78, Issue , pp. -. DOI: 10.1016/j.bmc.2022.117135
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Dual functional antioxidant and butyrylcholinesterase inhibitors for the treatment of Alzheimer's disease: Design, synthesis and evaluation of novel melatonin-alkylbenzylamine hybrids
Author: Liu, Peng; Cheng, Maojun; Guo, Jie; Cao, Duanyuan; Luo, Jinchong; Wan, Yang; Fang, Yuanying; Jin, Yi; Xie, Sai-Sai; Liu, Jing
Journal: BIOORGANIC & MEDICINAL CHEMISTRY. 2023; Vol. 78, Issue , pp. -. DOI: 10.1016/j.bmc.2022.117146
