Genome Biology

Genome Biology

基因组生物学

  • 1区 中科院分区
  • Q1 JCR分区

高引用文章

文章名称 引用次数
SCANPY: large-scale single-cell gene expression data analysis 233
OrthoFinder: phylogenetic orthology inference for comparative genomics 143
Improved metagenomic analysis with Kraken 2 119
Prediction of functional microRNA targets by integrative modeling of microRNA binding and target expression data 112
Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression 110
PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells 86
Ten things you should know about transposable elements 82
From squiggle to basepair: computational approaches for improving nanopore sequencing read accuracy 69
Cell Hashing with barcoded antibodies enables multiplexing and doublet detection for single cell genomics 64
Performance of neural network basecalling tools for Oxford Nanopore sequencing 63
Cytoscape Automation: empowering workflow-based network analysis 63
Expanded base editing in rice and wheat using a Cas9-adenosine deaminase fusion 63
Translation of the circular RNA circ-catenin promotes liver cancer cell growth through activation of the Wnt pathway 62
A novel long noncoding RNA HOXC-AS3 mediates tumorigenesis of gastric cancer by binding to YBX1 58
The 3D Genome Browser: a web-based browser for visualizing 3D genome organization and long-range chromatin interactions 54
SCoPE-MS: mass spectrometry of single mammalian cells quantifies proteome heterogeneity during cell differentiation 53
Exosomal miR-196a derived from cancer-associated fibroblasts confers cisplatin resistance in head and neck cancer through targeting CDKN1B and ING5 52
DNA methylation aging clocks: challenges and recommendations 50
Current status and applications of genome-scale metabolic models 50
RNA virus interference via CRISPR/Cas13a system in plants 48
Gene duplication and evolution in recurring polyploidization-diploidization cycles in plants 46
A novel FLI1 exonic circular RNA promotes metastasis in breast cancer by coordinately regulating TET1 and DNMT1 46
EmptyDrops: distinguishing cells from empty droplets in droplet-based single-cell RNA sequencing data 45
Ythdf2-mediated m(6)A mRNA clearance modulates neural development in mice 41
SKESA: strategic k-mer extension for scrupulous assemblies 41
Identification of transcription factor binding sites using ATAC-seq 40
A large-scale whole-genome sequencing analysis reveals highly specific genome editing by both Cas9 and Cpf1 (Cas12a) nucleases in rice 39
DeepCRISPR: optimized CRISPR guide RNA design by deep learning 39
Linking the International Wheat Genome Sequencing Consortium bread wheat reference genome sequence to wheat genetic and phenomic data 39
Comprehensive evaluation of structural variation detection algorithms for whole genome sequencing 36
Epigenetic modifications of histones in cancer 36
An amplicon-based sequencing framework for accurately measuring intrahost virus diversity using PrimalSeq and iVar 35
SUPPA2: fast, accurate, and uncertainty-aware differential splicing analysis across multiple conditions 34
Applications and potential of genome editing in crop improvement 32
CHESS: a new human gene catalog curated from thousands of large-scale RNA sequencing experiments reveals extensive transcriptional noise 31
HiGlass: web-based visual exploration and analysis of genome interaction maps 31
Interaction between the microbiome and TP53 in human lung cancer 31
Analysis of error profiles in deep next-generation sequencing data 30
A comparison of automatic cell identification methods for single-cell RNA sequencing data 30
RNA m(6)A methylation participates in regulation of postnatal development of the mouse cerebellum 29
RaGOO: fast and accurate reference-guided scaffolding of draft genomes 29
Accuracy assessment of fusion transcript detection via read-mapping and de novo fusion transcript assembly-based methods 29
KrakenUniq: confident and fast metagenomics classification using unique k-mer counts 28
Transcriptome assembly from long-read RNA-seq alignments with StringTie2 28
Impact of transposable elements on genome structure and evolution in bread wheat 28
Chromosome evolution at the origin of the ancestral vertebrate genome 27
Frequent intra- and inter-species introgression shapes the landscape of genetic variation in bread wheat 25
Livestock 2.0-genome editing for fitter, healthier, and more productive farmed animals 24
Molecular evolutionary trends and feeding ecology diversification in the Hemiptera, anchored by the milkweed bug genome 24
Observation weights unlock bulk RNA-seq tools for zero inflation and single-cell applications 24