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Identifying the Transcriptional Drivers of Metastasis Embedded within Localized Melanoma
Author: Suresh, Shruthy; Rabbie, Roy; Garg, Manik; Lumaquin, Dianne; Huang, Ting -Hsiang; Montal, Emily; Ma, Yilun; Cruz, Nelly M.; Tang, Xinran; Nsengimana, Jeremie; Newton-Bishop, Julia; Hunter, Miranda V.; Zhu, Yuxin; Chen, Kevin; de Stanchina, Elisa; Adams, David J.; White, Richard M.
Journal: CANCER DISCOVERY. 2023; Vol. 13, Issue 1, pp. 194-215. DOI: 10.1158/2159-8290.CD-22-0427
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A Molecular Switch between Mammalian MLL Complexes Dictates Response to Menin-MLL Inhibition
Author: Soto-Feliciano, Yadira M.; Sanchez-Rivera, Francisco J.; Perner, Florian; Barrows, Douglas W.; Kastenhuber, Edward R.; Ho, Yu-Jui; Carroll, Thomas; Xiong, Yijun; Anand, Disha; Soshnev, Alexey A.; Gates, Leah; Beytagh, Mary Clare; Cheon, David; Gu, Shengqing; Liu, X. Shirley; Krivtsov, Andrei, V; Meneses, Maximiliano; de Stanchina, Elisa; Stone, Richard M.; Armstrong, Scott A.; Lowe, Scott W.; Allis, C. David
Journal: CANCER DISCOVERY. 2023; Vol. 13, Issue 1, pp. 146-169. DOI: 10.1158/2159-8290.CD-22-0416
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OncoLoop: A Network-Based Precision Cancer Medicine Framework
Author: Vasciaveo, Alessandro; Arriaga, Juan Martin; de Almeida, Francisca Nunes; Zou, Min; Douglass Jr, Eugene F.; Picech, Florencia; Shibata, Maho; Rodriguez-Calero, Antonio; de Brot, Simone; Mitrofanova, Antonina; Chua, Chee Wai; Karan, Charles; Realubit, Ronald; Pampou, Sergey; Kim, Jaime Y.; Afari, Stephanie N.; Mukhammadov, Timur; Zanella, Luca; Corey, Eva; Alvarez, Mariano J.; Rubin, Mark A.; Shen, Michael M.; Califano, Andrea; Abate-Shen, Cory
Journal: CANCER DISCOVERY. 2023; Vol. 13, Issue 2, pp. 386-409. DOI: 10.1158/2159-8290.CD-22-0342
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Discovery of Targets for Immune-Metabolic Antitumor Drugs Identifi es Estrogen-Related Receptor Alpha
Author: Sahu, Avinash; Wang, Xiaoman; Munson, Phillip; Klomp, Jan P. G.; Wang, Xiaoqing; Gu, Shengqing Stan; Han, Ya; Qian, Gege; Nicol, Phillip; Zeng, Zexian; Wang, Chenfei; Tokheim, Collin; Zhang, Wubing; Fu, Jingxin; Wang, Jin; Nair, Nishanth Ulhas; Rens, Joost A. P.; Bourajjaj, Meriem; Jansen, Bas; Leenders, Inge; Lemmers, Jaap; Musters, Mark; van Zanten, Sanne; van Zelst, Laura; Worthington, Jenny; Lu, Jun S.; Juric, Dejan; Meyer, Clifford A.; Oubrie, Arthur; Liu, X. Shirley; Fisher, David E.; Flaherty, Keith T.
Journal: CANCER DISCOVERY. 2023; Vol. 13, Issue 3, pp. 672-701. DOI: 10.1158/2159-8290.CD-22-0244
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Targeting Microglial Metabolic Rewiring Synergizes with Immune-Checkpoint Blockade Therapy for Glioblastoma
Author: Ye, Zengpanpan; Ai, Xiaolin; Yang, Kailin; Yang, Zhengnan; Fei, Fan; Liao, Xiaoling; Qiu, Zhixin; Gimple, Ryan C.; Yuan, Huairui; Huang, Hao; Gong, Yanqiu; Xiao, Chaoxin; Yue, Jing; Huang, Liang; Saulnier, Olivier; Wang, Wei; Zhang, Peidong; Dai, Lunzhi; Wang, Xin; Wang, Xiuxing; Ha Ahn, Young; You, Chao; Xu, Jianguo; Wan, Xiaoxiao; Taylor, Michael D.; Zhao, Linjie; Rich, Jeremy N.; Zhou, Shengtao
Journal: CANCER DISCOVERY. 2023; Vol. 13, Issue 4, pp. 974-1001. DOI: 10.1158/2159-8290.CD-22-0455
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Antibody-Exatecan Conjugates with a Novel Self-immolative Moiety Overcome Resistance in Colon and Lung Cancer
Author: Weng, Weining; Meng, Tao; Zhao, Qianqian; Shen, Yi; Fu, Guoxiang; Shi, Jing; Zhang, Yue; Wang, Zhaohui; Wang, Mingqiao; Pan, Rong; Ma, Linjie; Chen, Caiwei; Wang, Lijun; Zhou, Biao; Zhang, Hui; Pu, Junyi; Zhang, Jianjian; Hu, Yi Peter; Hua, Guoqiang; Qian, Yu; Liu, Shu-Hui; Hu, Wenhao; Meng, Xun
Journal: CANCER DISCOVERY. 2023; Vol. 13, Issue 4, pp. 950-973. DOI: 10.1158/2159-8290.CD-22-1368
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Mutant and Wild-Type Isocitrate Dehydrogenase 1 Share Enhancing Mechanisms Involving Distinct Tyrosine Kinase Cascades in Cancer.
Author: Chen D1,2, Xia S#1,2, Wang M#1,2,3, Lin R1,2, Li Y2,4, Mao H2,4, Aguiar M5, Famulare CA6, Shih AH6, Brennan CW6, Gao X1,2, Pan Y1,7, Liu S1,8, Fan J2,9, Jin L1,2, Song L10, Zhou A10, Mukherjee J11, Pieper RO11, Mishra A12, Peng J12, Arellano M1,2, Blum WG1,2, Lonial S1,2, Boggon TJ13, Levine RL14, Chen J#15,2.
Journal: Cancer Discov. 2019 Mar 12. doi: 10.1158/2159-8290.CD-18-1040. [Epub ahead of print]
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Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression.
Author: Wang G, Lu X, Dey P, Deng P, Wu CC, Jiang S, Fang Z, Zhao K, Konaparthi R, Hua S, Zhang J, Li-Ning-Tapia EM, Kapoor A, Wu CJ, Patel NB, Guo Z, Ramamoorthy V, Tieu TN, Heffernan T, Zhao D, Shang X, Khadka S, Hou P, Hu B, Jin EJ, Yao W, Pan X, Ding Z, Shi Y, Li L, Chang Q, Troncoso P, Logothetis CJ, McArthur MJ, Chin L, Wang YA, DePinho RA.
Journal: Cancer Discov. 2016 Jan;6(1):80-95. doi: 10.1158/2159-8290.CD-15-0224. Epub 2015 Dec 23.
