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Design, synthesis and evaluation of novel substituted 4,5,6,7-tetrahydrobenzo[b]thiophene derivatives as potential anti-ZIKV agent
Author: Bian, Cong; Gao, Yixue; Zhao, Shuwen; Zhao, Yelin; Wu, Quchen; Zhou, Rui; Chen, Xiaofang; Cen, Shan
Journal: BIOORGANIC CHEMISTRY. 2026; Vol. 176, Issue , pp. -. DOI: 10.1016/j.bioorg.2026.109833
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DecipHering the synergistic inhibition mechanism of xanthine oxidase by Myricetin and allopurinol: Insights from inhibition kinetics, thermodynamics, and molecular dynamic simulation
Author: Yao, Yuanyong; Ye, Jiaxing; Chen, Lihong; Ma, Ao; Pang, Xinyan; Song, Shiming; Zhang, Meng; Chen, Shixue; Yang, Hai
Journal: BIOORGANIC CHEMISTRY. 2026; Vol. 176, Issue , pp. -. DOI: 10.1016/j.bioorg.2026.109832
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Meloaxilines A-E, five unprecedented monoterpenoid indole alkaloids from Melodinus axillaris, suppress colorectal cancer by targeting the iron metabolism pathwa
Author: Du, Kai-Cheng; Li, Guo-Chang; Li, Yu-Hang; Xu, Xun-Bo; Hua, Hui-Ming; Kongkatitham, Virunh; Wang, Yu-Meng; Rojsitthisak, Pornchai; Meng, Da-Li
Journal: BIOORGANIC CHEMISTRY. 2026; Vol. 176, Issue , pp. -. DOI: 10.1016/j.bioorg.2026.109845
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Decade of research on insect chitinase inhibitors: insights from molecular structure to biological functio
Author: Zhang, Yan-jun; Ai, Yin; Li, Jian-yang; Dong, Yan-hong; Zhang, Jian-jun
Journal: BIOORGANIC CHEMISTRY. 2026; Vol. 176, Issue , pp. -. DOI: 10.1016/j.bioorg.2026.109844
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Discovery of the first-in-class highly potent FXR/HSD17B13 dual modulator for the treatment of metabolic dysfunction-associated steatohepatiti
Author: Xu, Xue; Liu, Yuxia; Yang, Zhongcheng; Wu, Zhican; Guo, Wenli; Yang, Min; Xia, Jiajing; Wu, Chuanbin; Li, Zheng; Cheng, Guohua
Journal: BIOORGANIC CHEMISTRY. 2026; Vol. 176, Issue , pp. -. DOI: 10.1016/j.bioorg.2026.109843
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Prodigiosin inhibits proliferation and metastasis in head and neck squamous cell carcinoma: insights from phenotypic validation and network pharmacolog
Author: Mao, Xinhui; Huang, Huiying; Zhao, Limin; Zhou, Teng; Han, Jinlu; Yuan, Xiaohui; Li, Feiran; Wang, Zhenwei; Liang, Simin; Hsueh, Chi-Yao; Lau, Hui-Ching; Zhang, Ming
Journal: BIOORGANIC CHEMISTRY. 2026; Vol. 176, Issue , pp. -. DOI: 10.1016/j.bioorg.2026.109841
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Benzalkonium chloride and its derivatives as 5α-reductase 1 inhibitors to disrupt neurosteroid biosynthesi
Author: Huang, Yinghao; Ding, Chentao; Wang, Shaowei; Qi, Shufang; Zhu, He; Wang, Yiyan; Ge, Ren-shan; Liu, Yi; Cheng, Jing
Journal: BIOORGANIC CHEMISTRY. 2026; Vol. 176, Issue , pp. -. DOI: 10.1016/j.bioorg.2026.109850
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Dual organelle targeting type I/II photosensitizer triggers ferroptosis-like/ apoptosis for photodynamic immunotherap
Author: Duan, Zeyu; Deng, Lidong; Li, Qiyan; Li, Lie; Li, Chengmei; Zhao, Yubin; Liu, Ruiyuan
Journal: BIOORGANIC CHEMISTRY. 2026; Vol. 176, Issue , pp. -. DOI: 10.1016/j.bioorg.2026.109852
