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Novel 4-Amino-Quinazoline moieties ligated Platinum(IV) prodrugs overcome cisplatin resistance in EGFRWT human lung cancer
Author: Li, Rui; Zhao, Weiheng; Jin, Chen; Xiong, Huihua
Journal: BIOORGANIC CHEMISTRY. 2023; Vol. 135, Issue , pp. -. DOI: 10.1016/j.bioorg.2023.106499
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H2S-activated fluorescent probe enables dual-channel fluorescence tracking of drug release in tumor cells
Author: Liu, Caiyun; Zhang, Yan; Sun, Weimin; Zhu, Hanchuang; Su, Meijun; Wang, Xin; Rong, Xiaodi; Wang, Kun; Yu, Miaohui; Sheng, Wenlong; Zhu, Baocun
Journal: BIOORGANIC CHEMISTRY. 2023; Vol. 135, Issue , pp. -. DOI: 10.1016/j.bioorg.2023.106498
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Abietane diterpenoids from Orthosiphon wulfenioides with NLRP3 inflammasome inhibitory activity
Author: Tu, Wen-Chao; Zhao, Ying-Xin; Yang, Chang-Lin; Zhang, Xing-Jie; Li, Xiao-Li; Sakah, Kaunda-Joseph; Zhang, Rui-Han; Xiao, Wei-Lie; Liu, Mei-Feng
Journal: BIOORGANIC CHEMISTRY. 2023; Vol. 136, Issue , pp. -. DOI: 10.1016/j.bioorg.2023.106534
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Discovery and structural optimization of 3-O-beta-Chacotriosyl betulonic acid saponins as potent fusion inhibitors of Omicron virus infections
Author: Liu, Mingjian; Wang, Jinshen; Wan, Xin; Li, Baixi; Guan, Mingming; Ning, Xiaoyun; Hu, Xiaojie; Li, Sumei; Liu, Shuwen; Song, Gaopeng
Journal: BIOORGANIC CHEMISTRY. 2023; Vol. 131, Issue , pp. -. DOI: 10.1016/j.bioorg.2022.106316
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Design and synthesis of 2-(2,2-diarylethyl)-cyclamine derivatives as M3 receptor antagonists and functional evaluation on COPD
Author: Zhao, Yaopeng; Wang, Jixia; Hou, Tao; Yu, Yancheng; Zhou, Han; Han, Yang; Cheng, Junxiang; Liu, Yanfang; Wang, Chaoran; Chen, Long; Liang, Xinmiao
Journal: BIOORGANIC CHEMISTRY. 2023; Vol. 131, Issue , pp. -. DOI: 10.1016/j.bioorg.2022.106308
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P-Y/G@NHs sensitizes non-small cell lung cancer cells to radiotherapy via blockage of the PI3K/AKT signaling pathway
Author: Zhang, Lu; Zhou, Chong; Zhou, Yun; Zhang, Wei; Hu, Xiang; Chen, Meng; Hui, Hui; Guo, Ling; Wu, Chengjun; Zhou, Juying; Yin, Haitao
Journal: BIOORGANIC CHEMISTRY. 2023; Vol. 131, Issue , pp. -. DOI: 10.1016/j.bioorg.2022.106317
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Synthesis of new phenoxymethylcoumarin clubbed 4-arylthiazolylhydra-zines as ?-glucosidase inhibitors and their kinetics and molecular docking studies
Author: ul Ain, Qurat; Saeed, Aamer; Khan, Ajmal; Ahmed, Atteeque; Ullah, Saeed; Halim, Sobia Ahsan; Irfan, Madiha; Tehzeeb, Arfa; El-Seedi, Hesham R.; Bin Muhsinah, Abdullatif; Al-Harrasi, Ahmed
Journal: BIOORGANIC CHEMISTRY. 2023; Vol. 131, Issue , pp. -. DOI: 10.1016/j.bioorg.2022.106302
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Discovery of two biotin-PEG4-diarylidenyl piperidone prodrugs as potent antitumor agents with good efficacy, limited toxicity, and low resistance
Author: Liu, Shuang-Qiang; Mao, Zhi-Chen; Xu, Yan-Li; Chen, Xiao-Man; Wang, Hui-Ling; Wang, Qi; Wei, Jian-Hua; Huang, Ri-Zhen; Zhang, Ye
Journal: BIOORGANIC CHEMISTRY. 2023; Vol. 131, Issue , pp. -. DOI: 10.1016/j.bioorg.2022.106323
